NtWRKY33 involved in senescence-induced nornicotine synthesis by activating NtE4 in tobacco

• Published in: Plant physiology and biochemistry Vol. 219; p. 109391
• Main Authors: Zhang, Xingzi, Wang, Jin, Wang, Yaqi, Jiang, Caihong, Yang, Aiguo, Li, Fengxia
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01.02.2025
• Subjects: Gene Expression Regulation, Plant; Nicotiana - genetics; Nicotiana - metabolism; Nicotine - analogs & derivatives; Nicotine - biosynthesis; Nicotine - metabolism; Nornicotine; NtE4; NtWRKY33; Plant Leaves - genetics; Plant Leaves - metabolism; Plant Proteins - genetics; Plant Proteins - metabolism; Plant Senescence - genetics; Plant Senescence - physiology; Plants, Genetically Modified; Senescence; Tobacco; Transcription Factors - genetics; Transcription Factors - metabolism; NtE4; Tobacco; Senescence; NtWRKY33; Nornicotine

Nornicotine is an undesirable alkaloid in tobacco due to its unpleasant taste and potential toxicity. The accumulation of nornicotine in tobacco leaves is related to the development of the leaves, with very low amounts present in green leaves and a dramatic increase after senescence. While it is kno...