Investigation of Association Between Insulin Injection Technique and Blood Glucose Control in Patients with Type 2 Diabetes
Background: The appropriate insulin injection skill is essential for optimal blood sugar control in patients with diabetes. However, the art of insulin injection is still not well understood in numerous medical centers. Objectives: This study was designed to determine the association between appropr...
Saved in:
Published in | International journal of endocrinology and metabolism Vol. 20; no. 4; p. e128392 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Brieflands
01.10.2022
|
Subjects | |
Online Access | Get full text |
ISSN | 1726-913X 1726-9148 |
DOI | 10.5812/ijem-128392 |
Cover
Abstract | Background: The appropriate insulin injection skill is essential for optimal blood sugar control in patients with diabetes. However, the art of insulin injection is still not well understood in numerous medical centers. Objectives: This study was designed to determine the association between appropriate insulin injection and blood glucose control in patients with type 2 diabetes in Yazd, Iran. Methods: This cross-sectional study was conducted on 301 patients with type 2 diabetes who referred to Diabetes Research Center in Yazd within August 2020 to February 2021. Based on simple random sampling, the subjects with inclusion criteria, such as age >18 years, using an insulin pen for at least 3 months, and self-injection, were selected. The insulin injection technique was evaluated by a 13-item researcher-made questionnaire. The total score of this questionnaire was 26, and its validity and reliability were confirmed. The data were analyzed using SPSS software (version 20). Results: The mean age of the participants was 59.83 ± 10.26 years, and 60.1% had primary school or less education. Most participants (87%) used a needle more than five times, and almost half of them (53.5%) did not rotate the injection sites properly. The patients who reported pain during injection had statically lower injection scores than others (17.90 vs. 19.38, P = 0.001). There was a significant negative correlation between insulin injection score with fasting blood sugar (β = -0.232, P < 0.001), two-hour postprandial glucose (β = -0.164, P = 0.005), and hemoglobin A1c (HbA1c) level (β = -0.263, P < 0.001). Conclusions: None of the patients in this study fully followed the principles of a proper injection, which can lead to pain during injection, lipohypertrophy, hyperglycemia, and increased HbA1c levels. |
---|---|
AbstractList | Background: The appropriate insulin injection skill is essential for optimal blood sugar control in patients with diabetes. However, the art of insulin injection is still not well understood in numerous medical centers. Objectives: This study was designed to determine the association between appropriate insulin injection and blood glucose control in patients with type 2 diabetes in Yazd, Iran. Methods: This cross-sectional study was conducted on 301 patients with type 2 diabetes who referred to Diabetes Research Center in Yazd within August 2020 to February 2021. Based on simple random sampling, the subjects with inclusion criteria, such as age >18 years, using an insulin pen for at least 3 months, and self-injection, were selected. The insulin injection technique was evaluated by a 13-item researcher-made questionnaire. The total score of this questionnaire was 26, and its validity and reliability were confirmed. The data were analyzed using SPSS software (version 20). Results: The mean age of the participants was 59.83 ± 10.26 years, and 60.1% had primary school or less education. Most participants (87%) used a needle more than five times, and almost half of them (53.5%) did not rotate the injection sites properly. The patients who reported pain during injection had statically lower injection scores than others (17.90 vs. 19.38, P = 0.001). There was a significant negative correlation between insulin injection score with fasting blood sugar (β = -0.232, P < 0.001), two-hour postprandial glucose (β = -0.164, P = 0.005), and hemoglobin A1c (HbA1c) level (β = -0.263, P < 0.001). Conclusions: None of the patients in this study fully followed the principles of a proper injection, which can lead to pain during injection, lipohypertrophy, hyperglycemia, and increased HbA1c levels. The appropriate insulin injection skill is essential for optimal blood sugar control in patients with diabetes. However, the art of insulin injection is still not well understood in numerous medical centers. This study was designed to determine the association between appropriate insulin injection and blood glucose control in patients with type 2 diabetes in Yazd, Iran. This cross-sectional study was conducted on 301 patients with type 2 diabetes who referred to Diabetes Research Center in Yazd within August 2020 to February 2021. Based on simple random sampling, the subjects with inclusion criteria, such as age >18 years, using an insulin pen for at least 3 months, and self-injection, were selected. The insulin injection technique was evaluated by a 13-item researcher-made questionnaire. The total score of this questionnaire was 26, and its validity and reliability were confirmed. The data were analyzed using SPSS software (version 20). The mean age of the participants was 59.83 ± 10.26 years, and 60.1% had primary school or less education. Most participants (87%) used a needle more than five times, and almost half of them (53.5%) did not rotate the injection sites properly. The patients who reported pain during injection had statically lower injection scores than others (17.90 vs. 19.38, P = 0.001). There was a significant negative correlation between insulin injection score with fasting blood sugar (β = -0.232, P < 0.001), two-hour postprandial glucose (β = -0.164, P = 0.005), and hemoglobin A1c (HbA1c) level (β = -0.263, P < 0.001). None of the patients in this study fully followed the principles of a proper injection, which can lead to pain during injection, lipohypertrophy, hyperglycemia, and increased HbA1c levels. |
Author | Mehrabbeik, Akram Shariati, Mahbobeh Mahmoudi Kohani, Hassan Ali Azizi, Reyhaneh Aghaee Meybody, Mohammadreza Namiranian, Nasim |
AuthorAffiliation | 1 Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran |
AuthorAffiliation_xml | – name: 1 Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran |
Author_xml | – sequence: 1 givenname: Akram surname: Mehrabbeik fullname: Mehrabbeik, Akram – sequence: 2 givenname: Nasim orcidid: 0000-0002-5133-6204 surname: Namiranian fullname: Namiranian, Nasim – sequence: 3 givenname: Reyhaneh surname: Azizi fullname: Azizi, Reyhaneh – sequence: 4 givenname: Mohammadreza surname: Aghaee Meybody fullname: Aghaee Meybody, Mohammadreza – sequence: 5 givenname: Mahbobeh surname: Shariati fullname: Shariati, Mahbobeh – sequence: 6 givenname: Hassan Ali surname: Mahmoudi Kohani fullname: Mahmoudi Kohani, Hassan Ali |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/36714187$$D View this record in MEDLINE/PubMed |
BookMark | eNptkcFLwzAUxoMoOqcn75K7VJu0TdKLMKfOgaCHCd5KmrxuGV0ym2xD_OftNh0qnt57vN_3JbzvGO1bZwGhMxJfZoLQKzOFWUSoSHK6hzqEUxblJBX7uz55PULH3k_jOGOCs0N0lDBOUiJ4B30M7RJ8MGMZjLPYVbjnvVNmO95AWAFYPLR-UZt1nYLabEagJta8LQBLq_FN7ZzGg3qhnAfcdzY0rsat4Ln1ARs8XpkwwaP3OWCKb40sIYA_QQeVrD2cftUuerm_G_UfosenwbDfe4xUQkiImEyrkiYpjTOeKiGF0pplLJUAWpKYpsCyKtaQZYrklFe5qhQjmealLnkpZdJF11vf-aKcgVbthxpZF_PGzGTzXjhpit8baybF2C2LXHCSs7g1OP9psFN-n7EFLraAapz3DVQ7hMTFOqRiHVKxDamlyR9ambA5ePu6qf_VfALp0JmH |
CitedBy_id | crossref_primary_10_1186_s12955_023_02123_z crossref_primary_10_4081_hls_2024_13065 crossref_primary_10_5812_jjcdc_147903 crossref_primary_10_3390_polym16172502 |
Cites_doi | 10.1177/0145721716648017 10.1371/journal.pone.0221462 10.1097/MD.0000000000025424 10.1016/j.jcte.2020.100217 10.17925/EE.2020.16.1.41 10.1007/s13300-019-0574-x 10.14341/dm9663 10.1177/2284240318773201 10.1016/S1262-3636(10)70002-1 10.1007/s13300-017-0315-y 10.1089/dia.2016.0334 10.1007/s13300-018-0522-1 10.1177/1932296815626723 10.1016/j.ijnurstu.2016.04.010 10.1016/j.mayocp.2016.06.011 10.1186/s40064-016-1978-y 10.1517/17425247.2011.614229 10.4103/ijem.IJEM_548_16 10.2337/dc21-S006 10.1016/j.dsx.2016.09.010 10.1016/j.diabet.2013.05.006 10.4103/ijem.IJEM_97_17 10.1016/j.jcte.2014.07.006 10.1007/s13300-017-0243-x 10.1007/s13300-018-0561-7 10.1155/2021/9921376 10.1016/j.jsps.2021.04.028 10.1007/s13300-020-00913-y |
ContentType | Journal Article |
Copyright | Copyright © 2022, International Journal of Endocrinology and Metabolism. Copyright © 2022, International Journal of Endocrinology and Metabolism 2022 |
Copyright_xml | – notice: Copyright © 2022, International Journal of Endocrinology and Metabolism. – notice: Copyright © 2022, International Journal of Endocrinology and Metabolism 2022 |
DBID | AAYXX CITATION NPM 5PM |
DOI | 10.5812/ijem-128392 |
DatabaseName | CrossRef PubMed PubMed Central (Full Participant titles) |
DatabaseTitle | CrossRef PubMed |
DatabaseTitleList | CrossRef PubMed |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1726-9148 |
ExternalDocumentID | PMC9871960 36714187 10_5812_ijem_128392 |
Genre | Journal Article |
GroupedDBID | --- 53G 5VS AAYXX ADBBV ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL CITATION C~G DIK DYU FRP HYE KQ8 M48 OK1 PGMZT RNS RPM TR2 NPM 5PM |
ID | FETCH-LOGICAL-c311t-6a4fb23420574c8a8cdd6564aeeda1024e65f0de55c1927f9cfc615d7bdb7baa3 |
IEDL.DBID | M48 |
ISSN | 1726-913X |
IngestDate | Thu Aug 21 18:38:35 EDT 2025 Thu Jan 02 22:54:02 EST 2025 Wed Aug 27 16:27:09 EDT 2025 Thu Apr 24 23:05:12 EDT 2025 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | true |
Issue | 4 |
Keywords | Blood Glucose Diabetes Injection Insulin |
Language | English |
License | Copyright © 2022, International Journal of Endocrinology and Metabolism. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c311t-6a4fb23420574c8a8cdd6564aeeda1024e65f0de55c1927f9cfc615d7bdb7baa3 |
ORCID | 0000-0002-5133-6204 |
OpenAccessLink | http://journals.scholarsportal.info/openUrl.xqy?doi=10.5812/ijem-128392 |
PMID | 36714187 |
ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_9871960 pubmed_primary_36714187 crossref_primary_10_5812_ijem_128392 crossref_citationtrail_10_5812_ijem_128392 |
PublicationCentury | 2000 |
PublicationDate | 2022-10-01 |
PublicationDateYYYYMMDD | 2022-10-01 |
PublicationDate_xml | – month: 10 year: 2022 text: 2022-10-01 day: 01 |
PublicationDecade | 2020 |
PublicationPlace | Netherlands |
PublicationPlace_xml | – name: Netherlands |
PublicationTitle | International journal of endocrinology and metabolism |
PublicationTitleAlternate | Int J Endocrinol Metab |
PublicationYear | 2022 |
Publisher | Brieflands |
Publisher_xml | – name: Brieflands |
References | key-A128392REF10-10 key-A128392REF12-12 key-A128392REF6-6 Rostambeigy P (key-A128392REF11-11) 2014; 5 key-A128392REF14-14 key-A128392REF7-7 key-A128392REF4-4 key-A128392REF16-16 key-A128392REF5-5 key-A128392REF18-18 key-A128392REF9-9 key-A128392REF8-8 key-A128392REF25-25 key-A128392REF27-27 key-A128392REF21-21 key-A128392REF23-23 key-A128392REF29-29 key-A128392REF2-2 key-A128392REF3-3 key-A128392REF30-30 key-A128392REF1-1 key-A128392REF19-19 key-A128392REF15-15 key-A128392REF17-17 key-A128392REF26-26 key-A128392REF28-28 key-A128392REF20-20 key-A128392REF22-22 key-A128392REF24-24 Shon D (key-A128392REF13-13) 2020 |
References_xml | – ident: key-A128392REF30-30 doi: 10.1177/0145721716648017 – ident: key-A128392REF10-10 doi: 10.1371/journal.pone.0221462 – ident: key-A128392REF1-1 doi: 10.1097/MD.0000000000025424 – ident: key-A128392REF27-27 doi: 10.1016/j.jcte.2020.100217 – ident: key-A128392REF15-15 doi: 10.17925/EE.2020.16.1.41 – ident: key-A128392REF4-4 doi: 10.1007/s13300-019-0574-x – ident: key-A128392REF28-28 doi: 10.14341/dm9663 – volume: 5 start-page: 143 issue: 2 year: 2014 ident: key-A128392REF11-11 publication-title: Adv Biores. – ident: key-A128392REF2-2 doi: 10.1177/2284240318773201 – ident: key-A128392REF3-3 doi: 10.1016/S1262-3636(10)70002-1 – ident: key-A128392REF26-26 doi: 10.1007/s13300-017-0315-y – ident: key-A128392REF18-18 doi: 10.1089/dia.2016.0334 – ident: key-A128392REF8-8 doi: 10.1007/s13300-018-0522-1 – ident: key-A128392REF22-22 doi: 10.1177/1932296815626723 – ident: key-A128392REF19-19 doi: 10.1016/j.ijnurstu.2016.04.010 – ident: key-A128392REF5-5 doi: 10.1016/j.mayocp.2016.06.011 – ident: key-A128392REF7-7 doi: 10.1186/s40064-016-1978-y – ident: key-A128392REF29-29 doi: 10.1517/17425247.2011.614229 – ident: key-A128392REF20-20 doi: 10.4103/ijem.IJEM_548_16 – ident: key-A128392REF14-14 doi: 10.2337/dc21-S006 – ident: key-A128392REF21-21 doi: 10.1016/j.dsx.2016.09.010 – ident: key-A128392REF9-9 doi: 10.1016/j.diabet.2013.05.006 – ident: key-A128392REF16-16 doi: 10.4103/ijem.IJEM_97_17 – ident: key-A128392REF17-17 doi: 10.1016/j.jcte.2014.07.006 – ident: key-A128392REF23-23 doi: 10.1007/s13300-017-0243-x – ident: key-A128392REF12-12 doi: 10.1007/s13300-018-0561-7 – year: 2020 ident: key-A128392REF13-13 publication-title: Insulin Injection Re-Education for Improved Glycemic Control. – ident: key-A128392REF25-25 doi: 10.1155/2021/9921376 – ident: key-A128392REF6-6 doi: 10.1016/j.jsps.2021.04.028 – ident: key-A128392REF24-24 doi: 10.1007/s13300-020-00913-y |
SSID | ssj0056876 |
Score | 2.260146 |
Snippet | Background: The appropriate insulin injection skill is essential for optimal blood sugar control in patients with diabetes. However, the art of insulin... The appropriate insulin injection skill is essential for optimal blood sugar control in patients with diabetes. However, the art of insulin injection is still... |
SourceID | pubmedcentral pubmed crossref |
SourceType | Open Access Repository Index Database Enrichment Source |
StartPage | e128392 |
Title | Investigation of Association Between Insulin Injection Technique and Blood Glucose Control in Patients with Type 2 Diabetes |
URI | https://www.ncbi.nlm.nih.gov/pubmed/36714187 https://pubmed.ncbi.nlm.nih.gov/PMC9871960 |
Volume | 20 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1NT8JAEN0gJsaL8Vv8IHvgZFJst7v9OBkhIpqUcKAJnppttxshpChgovHPO9stDTWcvLSHzl5m2743ndc3CLU8z-KEp8yQjPiqQGFGbEnTELZJpCuEKfPJc8HA6Yf0ZczGNbQexlkkcLm1tFPzpMLFrP318X0PDzzw1zYDfLqbTFN4nRAF9TtoFyDJUVVYQMt2AnO8fMocgLWjWs1j_aPe38UVaCrxqKqV3ACf3iE6KFgjftDbfIRqaXaM9oKiL36CfjbsMuYZnku8kXbc0Vos_Kx153Ce5gKsDI_WDq6YZwJ3lIgdP2kRO-5qETuGBUNtvrrE6qstVqUrJrjQ0ixPUdh7HHX7RjFWwUhsy1oZDqcyJjYlQNVo4nEvEQJYHeUAlxz4Bk0dJk2RMpYA_XOln8gEeI9wYxG7Mef2Gapn8yy9QNixLco5FyRvkQrCfcv3lMGLmwB1IWkD3a4zGiWF57gafTGLoPZQ6Y9U-iOd_gZqlcHv2mpje9i53pEyyHZci1qe20BuZa_KAGWhXb2STd5yK20f6kWo4S7_vfIK7RP1Q0Qu77tG9dXiM70BmrKKm0DQX8NmfiPCcTAMfgE_Uu5n |
linkProvider | Scholars Portal |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Investigation+of+Association+Between+Insulin+Injection+Technique+and+Blood+Glucose+Control+in+Patients+with+Type+2+Diabetes&rft.jtitle=International+journal+of+endocrinology+and+metabolism&rft.au=Mehrabbeik%2C+Akram&rft.au=Namiranian%2C+Nasim&rft.au=Azizi%2C+Reyhaneh&rft.au=Aghaee+Meybody%2C+Mohammadreza&rft.date=2022-10-01&rft.pub=Brieflands&rft.issn=1726-913X&rft.eissn=1726-9148&rft.volume=20&rft.issue=4&rft_id=info:doi/10.5812%2Fijem-128392&rft.externalDocID=PMC9871960 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1726-913X&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1726-913X&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1726-913X&client=summon |