The therapeutic potential of Rosiglitazone in modulating scar formation through PPAR-γ pathway - Fang, Qing-qing; Gu, Yang-jun; Wang, Yong; Wang, Zheng-cai; Lin, Xiao-ying; Guo, Kai; Zhuang, Ze-ming; Zhong, Xin-cao; Zhang, Li-yun; Chen, Jian; Tan, Wei-qiang (European journal of pharmacology, 2025)
Keywords: 3T3-L1 Cells; Animals; Cicatrix - drug therapy; Cicatrix - metabolism; Cicatrix - pathology; Fibroblasts - drug effects; Fibroblasts - metabolism; Fibroblasts - pathology; Fibrosis; Glycolipid metabolism; Inflammation; Inflammatory cytokines; Lipid Metabolism - drug effects; Male; Mice; NIH 3T3 Cells; PPAR gamma - agonists; PPAR gamma - metabolism; PPAR-γ; Rats; Rats, Sprague-Dawley; Rosiglitazone; Rosiglitazone - pharmacology; Rosiglitazone - therapeutic use; Scar formation; Signal Transduction - drug effects; Transforming Growth Factor beta1 - pharmacology; Rosiglitazone; Scar formation; Inflammation; Glycolipid metabolism; Inflammatory cytokines; PPAR-γ