Synthesis and Spectral Characterization of Some Novel Thiazolyl-Pyrazoline Derivatives Containing 1,2,3-Triazole Moiety

• Published in: Phosphorus, sulfur, and silicon and the related elements Vol. 186; no. 2; pp. 263 - 270
• Main Authors: Shi, Hai, Liu, Fang-Ming, Shen, Song-Wei
• Format: Journal Article
• Language: English
• Published: ABINGDON Taylor & Francis 01.02.2011; Taylor & Francis Ltd
• Subjects: 1,2,3-triazole; Aromatic compounds; Carbothioamide; Chemical analysis; Chemistry; Chemistry, Inorganic & Nuclear; Chemistry, Organic; NMR; Nuclear magnetic resonance; Physical Sciences; pyrazoline; Science & Technology; thiazole; Triazoles; 1,3-DIPOLAR CYCLOADDITION REACTION; ANTIDEPRESSANT; Carbothioamide; 2-PHENYL-1,2,3-TRIAZOLE; thiazole; ANTIBACTERIAL; AGENTS; pyrazoline; INHIBITORS; 1,2,3-triazole

A series of novel 3-aryl-5-(2-aryl-1,2,3-triazol-4-yl)-1-(4-aryl-2-thiazoyl)-pyrazolines 6a-6r were synthesized using 2-aryl-4-formyl-1,2,3-triazoles 1a,b as the starting materials. Thus, reacting 1a,b with 1-arylethanones 2a-2c gave 1-aryl-3-(2-aryl-1,2,3-triazol-4-yl)-2-propen-1-ones 3a-3f. The re...