Early influenza virus exposure shapes the B cell response to influenza vaccination in individuals 50 years later - Spangler, Abby; Shimberg, Geoffrey D.; Mantus, Grace E.; Malek, Rory; Cominsky, Lauren Y.; Tsybovsky, Yaroslav; Li, Ning; Gillespie, Rebecca A.; Ravichandran, Michelle; Creanga, Adrian; Raab, Julie E.; Gajjala, Suprabhath R.; et al. (Immunity (Cambridge, Mass.), 2025)
Keywords: Adult; Antibodies, Viral - immunology; atypical B cells; B cells; B-Lymphocytes - immunology; Female; Hemagglutinin Glycoproteins, Influenza Virus - genetics; Hemagglutinin Glycoproteins, Influenza Virus - immunology; Humans; immunoglobulin repertoire; Immunologic Memory; imprinting; influenza vaccine; Influenza Vaccines - immunology; Influenza, Human - immunology; Influenza, Human - prevention & control; Influenza, Human - virology; Male; Memory B Cells - immunology; Middle Aged; Vaccination; Vaccines, DNA - immunology; influenza vaccine; H2; B cells; imprinting; atypical B cells; immunoglobulin repertoire