Intracranial calcifications in Post-mortem Computed Tomography and its forensic implications

• Published in: Australian journal of forensic sciences Vol. 57; no. 4; pp. 470 - 480
• Main Authors: Raj K, Karthi Vignesh, Gokul, G., Yadav, Abhishek, Abilash, S., Tyagi, Swati, Gupta, Sudhir K.
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 04.07.2025
• Subjects: choroid plexus calcification; intracranial calcification; pineal gland calcification; Postmortem Computed Tomography
• ISSN: 0045-0618; 1834-562X
• DOI: 10.1080/00450618.2024.2381526

Intracranial physiological calcifications are usually seen in Post-mortem Computed Tomography (PMCT) and are difficult to note with naked-eye examination during conventional autopsy. Studies on intracerebral calcifications in PMCT are few. Moreover, such studies may be of interest from the clinical perspective in order to compare physiological and pathological intracranial calcifications. Hence, the authors aimed to calculate the incidence of calcification of the pineal gland and choroid plexus in the lateral ventricle in brain PMCT and its association with age, sex, type of death, and manner of death. The authors studied 620 PMCT head scans of the deceased whose ages ranged from 2 months to 97 years (mean ± SD is 38.83 ± 15.91). A total of 59.68% had pineal calcification, and 47.42% had choroid plexus calcification with a male preponderance. A statistically significant association was present between the studied calcifications and age, sex, type of death, and manner of death. The calcification was higher in the pineal gland than in the choroid plexus until the fifth decade, and post fifth decade the choroid plexus calcification was more common. The presence of calcification was higher among the suicidal deaths when compared with the non-suicidal deaths with a statistically significant association (p < 0.05).