A comparison of the efficacy and safety of traditional Chinese medicine external treatment for the hyperemesis gravidarum: A protocol for systematic review and network meta-analysis
The symptoms of frequent nausea and vomiting, inability to eat, and fluid imbalance caused by hyperemesis gravidarum (HG) seriously impact the quality of life of pregnant women. In some serious cases, it is even necessary to terminate the pregnancy, and threatens the life of the pregnant woman. A gr...
Saved in:
Published in | Medicine (Baltimore) Vol. 99; no. 45; p. e23019 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Lippincott Williams & Wilkins
06.11.2020
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | The symptoms of frequent nausea and vomiting, inability to eat, and fluid imbalance caused by hyperemesis gravidarum (HG) seriously impact the quality of life of pregnant women. In some serious cases, it is even necessary to terminate the pregnancy, and threatens the life of the pregnant woman. A great many of studies have proved that HG can be effectively treated by traditional Chinese medicine (TCM) external treatment. Nevertheless, its relative effectiveness and safety haven't yet been confirmed because of the variety of TCM external treatment. Therefore, we will use the method of network meta-analysis to verify the effectiveness and safety of different types of TCM external treatment for the HG.
In this study, English and Chinese literatures that meet the requirements will be searched in EMBASE, PubMed, Cochrane Library, Web of Science, CnKI, VIP, Wanfang, and CBM. Regardless of whether blinding is used or not, all randomized controlled trials (RCTs) using TCM external treatment for the HG will be included. Then, Stata 16.0 will be used to conduct a series of pairwise meta-analysis. WinBUGS 1.4.3 and Stata 16.0 will be used to conduct Bayesian network meta-analysis to evaluate the relative results of different TCM external treatments for the HG. The quality included in the study will be evaluated through the classification of Grading of Recommendations Assessment, Development and Evaluation (GRADE).
This study will evaluate the effectiveness and safety of TCM external treatment for the HG according to the primary and secondary outcomes, and we rank different kinds of TCM external treatments in accordance with effectiveness. The primary outcomes are the intensity of nausea and vomiting. Secondary outcomes include quality of life, adverse outcome of pregnant women, adverse outcome of fetal, duration of hospitalization and so on.
This study will provide more convincing and detailed information of TCM external treatment for the HG, and the reference value for clinical treatment.
INPLASY 202090089. |
---|---|
AbstractList | Abstract
Background:
The symptoms of frequent nausea and vomiting, inability to eat, and fluid imbalance caused by hyperemesis gravidarum (HG) seriously impact the quality of life of pregnant women. In some serious cases, it is even necessary to terminate the pregnancy, and threatens the life of the pregnant woman. A great many of studies have proved that HG can be effectively treated by traditional Chinese medicine (TCM) external treatment. Nevertheless, its relative effectiveness and safety haven’t yet been confirmed because of the variety of TCM external treatment. Therefore, we will use the method of network meta-analysis to verify the effectiveness and safety of different types of TCM external treatment for the HG.
Methods:
In this study, English and Chinese literatures that meet the requirements will be searched in EMBASE, PubMed, Cochrane Library, Web of Science, CnKI, VIP, Wanfang, and CBM. Regardless of whether blinding is used or not, all randomized controlled trials (RCTs) using TCM external treatment for the HG will be included. Then, Stata 16.0 will be used to conduct a series of pairwise meta-analysis. WinBUGS 1.4.3 and Stata 16.0 will be used to conduct Bayesian network meta-analysis to evaluate the relative results of different TCM external treatments for the HG. The quality included in the study will be evaluated through the classification of Grading of Recommendations Assessment, Development and Evaluation (GRADE).
Results:
This study will evaluate the effectiveness and safety of TCM external treatment for the HG according to the primary and secondary outcomes, and we rank different kinds of TCM external treatments in accordance with effectiveness. The primary outcomes are the intensity of nausea and vomiting. Secondary outcomes include quality of life, adverse outcome of pregnant women, adverse outcome of fetal, duration of hospitalization and so on.
Conclusion:
This study will provide more convincing and detailed information of TCM external treatment for the HG, and the reference value for clinical treatment.
INPLASY registration number:
INPLASY 202090089. BACKGROUNDThe symptoms of frequent nausea and vomiting, inability to eat, and fluid imbalance caused by hyperemesis gravidarum (HG) seriously impact the quality of life of pregnant women. In some serious cases, it is even necessary to terminate the pregnancy, and threatens the life of the pregnant woman. A great many of studies have proved that HG can be effectively treated by traditional Chinese medicine (TCM) external treatment. Nevertheless, its relative effectiveness and safety haven't yet been confirmed because of the variety of TCM external treatment. Therefore, we will use the method of network meta-analysis to verify the effectiveness and safety of different types of TCM external treatment for the HG.METHODSIn this study, English and Chinese literatures that meet the requirements will be searched in EMBASE, PubMed, Cochrane Library, Web of Science, CnKI, VIP, Wanfang, and CBM. Regardless of whether blinding is used or not, all randomized controlled trials (RCTs) using TCM external treatment for the HG will be included. Then, Stata 16.0 will be used to conduct a series of pairwise meta-analysis. WinBUGS 1.4.3 and Stata 16.0 will be used to conduct Bayesian network meta-analysis to evaluate the relative results of different TCM external treatments for the HG. The quality included in the study will be evaluated through the classification of Grading of Recommendations Assessment, Development and Evaluation (GRADE).RESULTSThis study will evaluate the effectiveness and safety of TCM external treatment for the HG according to the primary and secondary outcomes, and we rank different kinds of TCM external treatments in accordance with effectiveness. The primary outcomes are the intensity of nausea and vomiting. Secondary outcomes include quality of life, adverse outcome of pregnant women, adverse outcome of fetal, duration of hospitalization and so on.CONCLUSIONThis study will provide more convincing and detailed information of TCM external treatment for the HG, and the reference value for clinical treatment.INPLASY REGISTRATION NUMBERINPLASY 202090089. The symptoms of frequent nausea and vomiting, inability to eat, and fluid imbalance caused by hyperemesis gravidarum (HG) seriously impact the quality of life of pregnant women. In some serious cases, it is even necessary to terminate the pregnancy, and threatens the life of the pregnant woman. A great many of studies have proved that HG can be effectively treated by traditional Chinese medicine (TCM) external treatment. Nevertheless, its relative effectiveness and safety haven't yet been confirmed because of the variety of TCM external treatment. Therefore, we will use the method of network meta-analysis to verify the effectiveness and safety of different types of TCM external treatment for the HG. In this study, English and Chinese literatures that meet the requirements will be searched in EMBASE, PubMed, Cochrane Library, Web of Science, CnKI, VIP, Wanfang, and CBM. Regardless of whether blinding is used or not, all randomized controlled trials (RCTs) using TCM external treatment for the HG will be included. Then, Stata 16.0 will be used to conduct a series of pairwise meta-analysis. WinBUGS 1.4.3 and Stata 16.0 will be used to conduct Bayesian network meta-analysis to evaluate the relative results of different TCM external treatments for the HG. The quality included in the study will be evaluated through the classification of Grading of Recommendations Assessment, Development and Evaluation (GRADE). This study will evaluate the effectiveness and safety of TCM external treatment for the HG according to the primary and secondary outcomes, and we rank different kinds of TCM external treatments in accordance with effectiveness. The primary outcomes are the intensity of nausea and vomiting. Secondary outcomes include quality of life, adverse outcome of pregnant women, adverse outcome of fetal, duration of hospitalization and so on. This study will provide more convincing and detailed information of TCM external treatment for the HG, and the reference value for clinical treatment. INPLASY 202090089. |
Author | Li, Changzhong Cai, Pingping Chen, Yin Zhan, Junyi Cao, Huanze Yan, Rugen Liu, Gongxue |
AuthorAffiliation | a The First Clinical College, Shandong University of Traditional Chinese Medicine b Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province c Xuyi County Hospital of Chinese Medicine, Xuyi, Jiangsu Province, China |
AuthorAffiliation_xml | – name: c Xuyi County Hospital of Chinese Medicine, Xuyi, Jiangsu Province, China – name: a The First Clinical College, Shandong University of Traditional Chinese Medicine – name: b Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province |
Author_xml | – sequence: 1 givenname: Rugen orcidid: 0000-0002-9783-7135 surname: Yan fullname: Yan, Rugen organization: The First Clinical College, Shandong University of Traditional Chinese Medicine – sequence: 2 givenname: Junyi surname: Zhan fullname: Zhan, Junyi organization: The First Clinical College, Shandong University of Traditional Chinese Medicine – sequence: 3 givenname: Gongxue surname: Liu fullname: Liu, Gongxue organization: The First Clinical College, Shandong University of Traditional Chinese Medicine – sequence: 4 givenname: Changzhong surname: Li fullname: Li, Changzhong organization: Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province – sequence: 5 givenname: Pingping surname: Cai fullname: Cai, Pingping organization: Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province – sequence: 6 givenname: Yin surname: Chen fullname: Chen, Yin organization: Xuyi County Hospital of Chinese Medicine, Xuyi, Jiangsu Province, China – sequence: 7 givenname: Huanze surname: Cao fullname: Cao, Huanze organization: The First Clinical College, Shandong University of Traditional Chinese Medicine |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33157951$$D View this record in MEDLINE/PubMed |
BookMark | eNpdUU1v1DAQtVAR3RZ-ARLykUtaO7bjhAPSagsUqRUXOFuOM-4aEjvY3i35Yfw_3G0pH3PxaN6b9zx6J-jIBw8IvaTkjJJOnl9fnJE_VTNCuydoRQVrKtE1_AitylRUspP8GJ2k9JUQymTNn6FjxqiQnaAr9HONTZhmHV0KHgeL8xYwWOuMNgvWfsBJW8jLAYp6cNkFr0e82ToPCfAEgzOlxfAjQ7xDcgSdJ_AZ2xAPcttlhggTJJfwTdR7N-i4m97gNZ5jyMGE8UBNS8ow6ewMjrB3cHuw95BvQ_xWjLKudDFYisxz9NTqMcGLh_cUfXn_7vPmsrr69OHjZn1VGUZJrgZLCOvbVvSCCMKBNX1D28FK2msp-rq2dS0aKTnjnQbWa9s3pOfSsJZD3Q7sFL291513fbnUlKuiHtUc3aTjooJ26l_Eu626CXslGy5FR4rA6weBGL7vIGU1uWRgHLWHsEuq5qKVdUMkK1R2TzUxpBTBPtpQou4CV9cX6v_Ay9arv3_4uPM7YfYL4ASthQ |
Cites_doi | 10.1097/AOG.0000000000002456 10.1067/mob.2002.122604 10.1159/000505637 10.1111/1471-0528.16227 10.1016/j.jogc.2016.08.009 10.1007/s00404-019-05192-y 10.1038/s41598-020-61114-y 10.1159/000477853 10.1080/17512433.2018.1530108 10.1016/j.ejogrb.2019.04.043 10.1016/j.ajog.2007.05.051 10.1016/j.jclinepi.2010.03.016 10.18637/jss.v032.i11 10.1111/1471-0528.15272 10.1136/bmj.g7647 |
ContentType | Journal Article |
Copyright | Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. 2020 |
Copyright_xml | – notice: Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. 2020 |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 5PM |
DOI | 10.1097/MD.0000000000023019 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic PubMed Central (Full Participant titles) |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | CrossRef MEDLINE - Academic MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1536-5964 |
EndPage | e23019 |
ExternalDocumentID | 10_1097_MD_0000000000023019 33157951 |
Genre | Journal Article |
GroupedDBID | --- .-D .XZ .Z2 01R 0R~ 354 40H 4Q1 4Q2 4Q3 5GY 5RE 5VS 71W 77Y 7O~ 8L- AAAAV AAGIX AAHPQ AAIQE AAMOA AAQKA AARTV AASCR AAWTL AAXQO AAYEP ABASU ABBUW ABCQX ABDIG ABFRF ABOCM ABVCZ ABXVJ ABZAD ACDDN ACEWG ACGFO ACGFS ACILI ACWDW ACWRI ACXJB ACXNZ ADGGA ADHPY ADNKB ADPDF AE6 AEFWE AENEX AFDTB AGOPY AHOMT AHQNM AHVBC AIJEX AINUH AJIOK AJNWD AJNYG AKULP ALMA_UNASSIGNED_HOLDINGS ALMTX AMJPA AMKUR AMNEI AOHHW AWKKM BQLVK CGR CS3 CUY CVF DIWNM DU5 E.X EBS ECM EEVPB EIF ERAAH EX3 F2K F2L F2M F2N F5P FCALG FD6 FIJ FL- GNXGY GQDEL GROUPED_DOAJ H0~ HLJTE HYE HZ~ H~9 IKREB IKYAY IN~ IPNFZ JK3 JK8 K8S KD2 KMI KQ8 L-C N9A NPM N~7 N~B O9- OAG OAH OB2 ODA OHH OK1 OL1 OLB OLG OLH OLU OLV OLY OLZ OPUJH OUVQU OVD OVDNE OVEED OVIDH OVLEI OWV OWW OWZ OXXIT P2P RIG RLZ RPM RXW S4R S4S TAF TEORI TSPGW UNMZH V2I VVN W3M WOQ WOW X3V X3W XYM YFH YOC ZA5 ZFV ZY1 AAYXX AJZMW CITATION 7X8 5PM |
ID | FETCH-LOGICAL-c310t-df003b885b50504e36b618df71ba75b22f2256774349ae3bafb60b47c384e28d3 |
IEDL.DBID | RPM |
ISSN | 0025-7974 |
IngestDate | Tue Sep 17 21:21:04 EDT 2024 Fri Aug 16 04:13:48 EDT 2024 Fri Aug 23 03:40:51 EDT 2024 Thu May 23 23:27:15 EDT 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 45 |
Language | English |
License | This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c310t-df003b885b50504e36b618df71ba75b22f2256774349ae3bafb60b47c384e28d3 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0002-9783-7135 |
OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647590/ |
PMID | 33157951 |
PQID | 2458726073 |
PQPubID | 23479 |
ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_7647590 proquest_miscellaneous_2458726073 crossref_primary_10_1097_MD_0000000000023019 pubmed_primary_33157951 |
PublicationCentury | 2000 |
PublicationDate | 2020-Nov-06 2020-11-06 20201106 |
PublicationDateYYYYMMDD | 2020-11-06 |
PublicationDate_xml | – month: 11 year: 2020 text: 2020-Nov-06 day: 06 |
PublicationDecade | 2020 |
PublicationPlace | United States |
PublicationPlace_xml | – name: United States – name: Hagerstown, MD |
PublicationTitle | Medicine (Baltimore) |
PublicationTitleAlternate | Medicine (Baltimore) |
PublicationYear | 2020 |
Publisher | Lippincott Williams & Wilkins |
Publisher_xml | – name: Lippincott Williams & Wilkins |
References | Lacasse (R20-20230916) 2008; 198 Magee (R21-20230916) 2002; 186 Tan (R3-20230916) 2020; 10 Shamseer (R18-20230916) 2015; 349 Koot (R5-20230916) 2018; 125 Campbell (R17-20230916) 2016; 38 Piwko (R7-20230916) 2013; 20 Fejzo (R8-20230916) 2020; 127 Cluver (R11-20230916) 2017; 9 Lin (R24-20230916) 2019; 98 Sridharan (R10-20230916) 2020; 33 Einarson (R4-20230916) 2013; 20 Tara (R13-20230916) 2020; 27 Sridharan (R14-20230916) 2018; 11 Wang (R19-20230916) 2020; 99 Salanti (R23-20230916) 2011; 64 London (R6-20230916) 2017; 100 (R16-20230916) 2018; 131 Loannidou (R2-20230916) 2019; 238 Agmon (R1-20230916) 2019; 300 Getahun (R9-20230916) 2019 Matthews (R12-20230916) 2015 Crainiceanu (R22-20230916) 2010; 32 |
References_xml | – volume: 131 start-page: e15 year: 2018 ident: R16-20230916 article-title: ACOG Practice Bulletin No. 189: nausea and vomiting of pregnancy publication-title: Obstet Gynecol doi: 10.1097/AOG.0000000000002456 – volume: 186 start-page: S232 year: 2002 ident: R21-20230916 article-title: Development of a health-related quality of life instrument for nausea and vomiting of pregnancy publication-title: Am J Obstet Gynecol doi: 10.1067/mob.2002.122604 contributor: fullname: Magee – year: 2019 ident: R9-20230916 article-title: Autism spectrum disorders in children exposed in utero to hyperemesis gravidarum publication-title: Am J Perinatol contributor: fullname: Getahun – volume: 9 start-page: CD010485 year: 2017 ident: R11-20230916 article-title: Interventions for treating genital Chlamydia trachomatis infection in pregnancy publication-title: Cochrane Database Syst Rev contributor: fullname: Cluver – volume: 27 start-page: 252 year: 2020 ident: R13-20230916 article-title: The effect of acupressure on the severity of nausea, vomiting, and retching in pregnant women: a randomized controlled trial publication-title: Complement Med Res doi: 10.1159/000505637 contributor: fullname: Tara – volume: 127 start-page: 983 year: 2020 ident: R8-20230916 article-title: A core outcome set for hyperemesis gravidarum studies is a small step in the right direction publication-title: BJOG doi: 10.1111/1471-0528.16227 contributor: fullname: Fejzo – volume: 38 start-page: 1127 year: 2016 ident: R17-20230916 article-title: The management of nausea and vomiting of pregnancy publication-title: J Obstet Gynaecol Can doi: 10.1016/j.jogc.2016.08.009 contributor: fullname: Campbell – volume: 300 start-page: 347 year: 2019 ident: R1-20230916 article-title: Hyperemesis gravidarum and adverse pregnancy outcomes publication-title: Arch Gynecol Obstet doi: 10.1007/s00404-019-05192-y contributor: fullname: Agmon – volume: 10 start-page: 4445 year: 2020 ident: R3-20230916 article-title: Taste, smell and food-related nausea and vomiting responses in hyperemesis gravidarum: a case-controlled study publication-title: Sci Rep doi: 10.1038/s41598-020-61114-y contributor: fullname: Tan – volume: 100 start-page: 161 year: 2017 ident: R6-20230916 article-title: Hyperemesis gravidarum: a review of recent literature publication-title: Pharmacology doi: 10.1159/000477853 contributor: fullname: London – start-page: CD007575 year: 2015 ident: R12-20230916 article-title: Interventions for nausea and vomiting in early pregnancy publication-title: Cochrane Database Syst Rev contributor: fullname: Matthews – volume: 11 start-page: 1143 year: 2018 ident: R14-20230916 article-title: Interventions for treating nausea and vomiting in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials publication-title: Expert Rev Clin Pharmacol doi: 10.1080/17512433.2018.1530108 contributor: fullname: Sridharan – volume: 238 start-page: 178 year: 2019 ident: R2-20230916 article-title: Predictive factors of hyperemesis gravidarum: a systematic review publication-title: Eur J Obstet Gynecol Reprod Biol doi: 10.1016/j.ejogrb.2019.04.043 contributor: fullname: Loannidou – volume: 198 start-page: 71.e1 year: 2008 ident: R20-20230916 article-title: Validity of a modified Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) scoring index to assess severity of nausea and vomiting of pregnancy publication-title: Am J Obstet Gynecol doi: 10.1016/j.ajog.2007.05.051 contributor: fullname: Lacasse – volume: 99 start-page: e20974 year: 2020 ident: R19-20230916 article-title: Different acupuncture therapies for spastic paralysis after stroke: a protocol for systematic review and network meta-analysis publication-title: Medicine (Madr) contributor: fullname: Wang – volume: 20 start-page: e149 year: 2013 ident: R7-20230916 article-title: Economic burden of nausea and vomiting of pregnancy in the USA publication-title: J Popul Ther Clin Pharmacol contributor: fullname: Piwko – volume: 64 start-page: 163 year: 2011 ident: R23-20230916 article-title: Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial publication-title: J Clin Epidemiol doi: 10.1016/j.jclinepi.2010.03.016 contributor: fullname: Salanti – volume: 20 start-page: e171 year: 2013 ident: R4-20230916 article-title: Quantifying the global rates of nausea and vomiting of pregnancy: a meta analysis publication-title: J Popul Ther Clin Pharmacol contributor: fullname: Einarson – volume: 32 start-page: 1 year: 2010 ident: R22-20230916 article-title: Bayesian Functional Data Analysis Using WinBUGS publication-title: J Stat Softw doi: 10.18637/jss.v032.i11 contributor: fullname: Crainiceanu – volume: 125 start-page: 1514 year: 2018 ident: R5-20230916 article-title: Variation in hyperemesis gravidarum definition and outcome reporting in randomised clinical trials: a systematic review publication-title: BJOG doi: 10.1111/1471-0528.15272 contributor: fullname: Koot – volume: 98 start-page: e14482 year: 2019 ident: R24-20230916 article-title: Acupuncture for fecal incontinence: protocol for a systematic review and data mining publication-title: Medicine (Madr) contributor: fullname: Lin – volume: 349 start-page: g7647 year: 2015 ident: R18-20230916 article-title: Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation publication-title: BMJ doi: 10.1136/bmj.g7647 contributor: fullname: Shamseer – volume: 33 start-page: 1405 year: 2020 ident: R10-20230916 article-title: Interventions for treating hyperemesis gravidarum: a network meta-analysis of randomized clinical trials publication-title: J Matern Fetal Neonatal Med contributor: fullname: Sridharan |
SSID | ssj0013724 |
Score | 2.3796444 |
Snippet | The symptoms of frequent nausea and vomiting, inability to eat, and fluid imbalance caused by hyperemesis gravidarum (HG) seriously impact the quality of life... Abstract Background: The symptoms of frequent nausea and vomiting, inability to eat, and fluid imbalance caused by hyperemesis gravidarum (HG) seriously impact... BACKGROUNDThe symptoms of frequent nausea and vomiting, inability to eat, and fluid imbalance caused by hyperemesis gravidarum (HG) seriously impact the... |
SourceID | pubmedcentral proquest crossref pubmed |
SourceType | Open Access Repository Aggregation Database Index Database |
StartPage | e23019 |
SubjectTerms | Bayes Theorem Female Humans Hyperemesis Gravidarum - psychology Hyperemesis Gravidarum - therapy Medicine, Chinese Traditional - adverse effects Medicine, Chinese Traditional - methods Meta-Analysis as Topic Network Meta-Analysis Pregnancy Quality of Life Randomized Controlled Trials as Topic Safety Study Protocol Systematic Review Systematic Reviews as Topic Treatment Outcome |
Title | A comparison of the efficacy and safety of traditional Chinese medicine external treatment for the hyperemesis gravidarum: A protocol for systematic review and network meta-analysis |
URI | https://www.ncbi.nlm.nih.gov/pubmed/33157951 https://search.proquest.com/docview/2458726073 https://pubmed.ncbi.nlm.nih.gov/PMC7647590 |
Volume | 99 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT-MwEB7xkNBeEI9ltzwqI3Hc0Dq24-SIaBFCCnAAxC3yU0TapqhpD_332EkdUbiRgy-Orcgz1nzzyDcAF0YRahSzEZMqjaizAFGKsY0SqywT2BO--Dhkfp_cPtO7V_a6ASz8C9MU7StZXlb_J5dV-dbUVr5P1CDUiQ0e82ueeJa64WATNjkhwUUPqQMe065Pq0PLgWoo44N81NIVto8D39iThhKCGc8YXrdM3-Dm16rJT2boZg92V_gRXbXfuQ8bpjqAnXyVIT-E5RVSXWtBNLXIATxkPE-EUEskKo1qYc182UzNhC7bWCDyfbRNbVDItaNAD426UnTk8G2z3ZvzXX1YsS5r5NsXlVrMFpPf8Hwzfrq-jVbtFSLlMN080tbdaJmmTDoUNKSGJDLBqbYcS8GZjGPr7nri4CGhmTBECiuToaRckZSaONXkCLaqaWX-Asow04IIP3iyHpFpng0NYVwLQ5WxPfgXjrZ4b1k0ipD9zkfFV6H04Dwcf-G03acwRGWmi7qIKUu5c8E46cGfVhzdhkGOPeBrgupe8Eza6zNOwRpG7ZVCHf945Qn8ir0j7uPNySlszWcLc-bQylz2Gy-_D9sPL-PxqN_o6ge6NOvb |
link.rule.ids | 230,315,733,786,790,870,891,27957,27958,53827,53829 |
linkProvider | National Library of Medicine |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV07b9swED6kKZB2adK3m6RlgYyRbYqkKI1BHnDbKOiQBNkEPhGhtRxY8uD--pKSKcTu1GjQQokAcTzedw9-B3BkFKFGMRsxqdKIOgsQpRjbKLHKMoE94YuPQ-ZXyeSGfr9jd1vAwl2YtmhfyXJY_Z4Oq_K-ra18mKpRqBMb_cxPeeJZ6sajZ_Dc6WvMg5Mekgc8pn2nVoeXA9lQxkf5WUdY2D0OfmNPG0oIZjxjeN02_QM4N-smHxmii124DUvo6k9-DReNHKo_G-yO_73GPXi1gqbopBt-DVumegM7-Sr5_haWJ0j1XQvRzCKHHZHxFBRCLZGoNKqFNc2yHZoLXXZhRuRbdJvaoJDGR4F5GvVV7shB53a6e-cW-4hlXdbId0YqtZgvpu_g5uL8-nQSrTo3RMrBxSbS1h0WMk2ZdABrTA1JZIJTbTmWgjMZx9YdI4lDnoRmwhAprEzGknJFUmriVJP3sF3NKvMRUIaZFkT4l-cBEpnm2dgQxrUwVBk7gOMgs-KhI-goQmI9Pys2pT2Ar0GuhVMknx0RlZkt6iKmLOXOu-NkAB86OfcThg0yAL62A_oPPEn3-oiTa0vWvZLjpyf_-QVeTK7zy-Ly29WPfXgZe3_fh7WTA9hu5gtz6EBRIz-3KvAXnL8LXQ |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV07b9swED60KRB0adNX6rZJWaBjZZkiKUpjEMdIHwoyNEDQReATEVrLhiUP7q8vKZlC7G7RoIUPgDge77sHvgP4bBShRjEbMamyiDoLEGUY2yi1yjKBPeGLj0MWV-nlDf12y27vtfrqivaVrMb1n_m4ru662srlXMWhTiy-Ls556lnqJvFS2_gxPHE6m-TBUQ8JBJ7QoVurw8yBcCjncTHtSQv7z0Fw7KlDCcGM5wzv2qf_QOd-7eQ9YzR7Dr_CMfoalN_jdSvH6u8ew-ODznkEz7YQFZ31U17AI1O_hMNim4R_BZszpIbuhWhhkcOQyHgqCqE2SNQaNcKadtMNrYSu-nAj8q26TWNQSOejwECNhmp35CB0t92dc4995LKpGuQ7JFVarNbz13Azu_h5fhltOzhEysHGNtLWPRoyy5h0QGtCDUllijNtOZaCM5kk1j0nqUOghObCECmsTCeSckUyapJMkzdwUC9q8xZQjpkWRPif5wMSueb5xBDGtTBUGTuCL0Fu5bIn6ihDgr2YlvsSH8GnINvSKZTPkojaLNZNmVCWceflcTKC417Ww4bhkoyA79yCYYIn694dcbLtSLu3snz34JUf4fB6Oit_fL36_h6eJt7t99Ht9AMctKu1OXHYqJWnnRb8AwAoDd0 |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+comparison+of+the+efficacy+and+safety+of+traditional+Chinese+medicine+external+treatment+for+the+hyperemesis+gravidarum&rft.jtitle=Medicine+%28Baltimore%29&rft.au=Yan%2C+Rugen&rft.au=Zhan%2C+Junyi&rft.au=Liu%2C+Gongxue&rft.au=Li%2C+Changzhong&rft.date=2020-11-06&rft.pub=Lippincott+Williams+%26+Wilkins&rft.issn=0025-7974&rft.eissn=1536-5964&rft.volume=99&rft.issue=45&rft_id=info:doi/10.1097%2FMD.0000000000023019&rft_id=info%3Apmid%2F33157951&rft.externalDBID=PMC7647590 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0025-7974&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0025-7974&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0025-7974&client=summon |