Protecting the ischemic spinal cord during aortic clamping. The influence of anesthetics and hypothermia

• Published in: Annals of surgery Vol. 215; no. 5; pp. 409 - 416
• Main Authors: Naslund, T C, Hollier, L H, Money, S R, Facundus, E C, Skenderis, 2nd, B S
• Format: Journal Article
• Language: English
• Published: United States 01.05.1992
• Subjects: Anesthetics; Animals; Aorta, Abdominal; Constriction; Halothane; Hypothermia, Induced; Intraoperative Care - methods; Ischemia - etiology; Ketamine; Paraplegia - prevention & control; Postoperative Complications - prevention & control; Rabbits; Reperfusion Injury - prevention & control; Spinal Cord - blood supply; Thiopental; Time Factors

Infrarenal circumaortic occlusion devices were operatively placed in 74 New Zealand white rabbits. Two days after operation the animals were randomly assigned to one of seven treatment groups: I, control, n = 23; II, halothane, n = 8; III, thiopental, n = 12; IV, ketamine (30 mg/kg intravenously), n...