Is the combined application of both drain-clamping and tranexamic acid superior to the single use of either application in patients with total-knee arthroplasty?: A meta-analysis of randomized controlled trials

• Published in: Medicine (Baltimore) Vol. 97; no. 36; p. e11573
• Main Authors: Han, Yan-Hong, Huang, He-Tao, Pan, Jian-Ke, Zeng, Ling-Feng, Liang, Gui-Hong, Liang, Hao-Dong, Yang, Wei-Yi, Guo, Da, Liu, Jun
• Format: Journal Article
• Language: English
• Published: United States Wolters Kluwer Health 01.09.2018
• Subjects: Antifibrinolytic Agents - therapeutic use; Arthroplasty, Replacement, Knee; Blood Loss, Surgical - prevention & control; Combined Modality Therapy; Constriction; Humans; Randomized Controlled Trials as Topic; Systematic Review and Meta-Analysis; Tranexamic Acid - therapeutic use

To compare the efficacy and safety of the combined application of both drain-clamping and tranexamic acid (TXA) versus the single use of either application in patients with total-knee arthroplasty (TKA). Databases (EMBASE, PubMed, Cochrane Library, Web of Sciences, the Google database, and the Ovid...