Potential novel proteomic biomarkers for diagnosis of vertebral osteomyelitis identified using an immunomics protein array technique: Two cases reports

• Published in: Medicine (Baltimore) Vol. 99; no. 43; p. e22852
• Main Authors: Chen, Chang-Hua, Chang, Ing-Lin, Wang, Shu-Hui, Yen, Hua-Cheng, Lin, Jen-Shiou, Lo, Shou-Chen, Huang, Chieh-Chen
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 23.10.2020
• Subjects: Aged; Autoantibodies - blood; Biomarkers - blood; Clinical Case Report; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Osteomyelitis - complications; Osteomyelitis - diagnosis; Osteomyelitis - microbiology; Protein Array Analysis; Spine - microbiology; Staphylococcal Infections - blood; Staphylococcal Infections - diagnosis; Staphylococcal Infections - microbiology; Staphylococcus aureus - isolation & purification

Although vertebral osteomyelitis (VO) is commonly associated with high morbidity and high recurrence rate, effective diagnostic and prognostic biomarkers of VO are still lacking. Case 1: a 60-year-old male had had upper back pain for 3 days. Case 2: a 71-year-old female presented upper back pain for...