Broad‐spectrum and sensitive screening of more than 1000 compounds in equine urine using liquid chromatography/high‐resolution mass spectrometry

• Published in: Rapid communications in mass spectrometry Vol. 38; no. 17; pp. 1 - 1593
• Main Authors: Uchida, Taiga, Kisugi, Takaya, Ishii, Hideaki, Yamada, Masayuki, Kinoshita, Kenji, Leung, Gary Ngai‐Wa
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 15.09.2024
• Subjects: Animals; Chromatography; Chromatography, Liquid - methods; Column chromatography; Doping in Sports - prevention & control; Horses - urine; Limit of Detection; Liquid chromatography; Mass spectrometry; Mass Spectrometry - methods; Negative ions; Reproducibility of Results; Scientific imaging; Screening; Solid Phase Extraction - methods; Substance Abuse Detection - methods; Substance Abuse Detection - veterinary; Target detection; Urine

Rationale To uphold the integrity of horseracing and equestrian sports, it is critical for an equine doping control laboratory to develop a comprehensive screening method to cover a wide range of target substances at the required detection levels in equine urine. Methods The procedure involved the e...