Site-Specific Dolasynthen Antibody–Drug Conjugates Exhibit Consistent Pharmacokinetic Profiles across a Wide Range of Drug-to-Antibody Ratios - Clardy, Susan M.; Uttard, Alex; Du, Bingfan; Catcott, Kalli C.; Lancaster, Kelly L.; Ditty, Elizabeth; Sadowsky, Jack; Zurita, Jeffrey; Malli, Naniye; Qin, LiuLiang; Bradley, Stephen P.; Avocetien, Kenneth; et al. (Molecular cancer therapeutics, 2024)
Keywords: Cysteine; Humans; Immunoconjugates - chemistry; Receptor, ErbB-2 - metabolism; Trastuzumab - chemistry; Trastuzumab - pharmacology; Xenograft Model Antitumor Assays