Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis - Apostolopoulou, Maria; Gordillo, Ruth; Koliaki, Chrysi; Gancheva, Sofia; Jelenik, Tomas; De Filippo, Elisabetta; Herder, Christian; Markgraf, Daniel; Jankowiak, Frank; Esposito, Irene; Schlensak, Matthias; Scherer, Philipp E.; et al. (Diabetes care, 2018)
Keywords: Abdominal surgery; Adult; Animals; c-Jun protein; Ceramide; Clamps; Correlation; Disease Progression; Fatty liver; Female; Glucose Clamp Technique; Humans; Inflammation; Inflammation - blood; Inflammation - metabolism; Inflammation - physiopathology; Insulin; Insulin resistance; Insulin Resistance - physiology; JNK protein; Lipid metabolism; Lipid peroxidation; Lipid Peroxidation - physiology; Lipids; Liver; Liver - chemistry; Liver - metabolism; Liver - pathology; Liver diseases; Male; Metabolism; Metabolites; Middle Aged; Mitochondria; Non-alcoholic Fatty Liver Disease - blood; Non-alcoholic Fatty Liver Disease - metabolism; Non-alcoholic Fatty Liver Disease - physiopathology; Obesity - blood; Obesity - metabolism; Obesity - physiopathology; Obesity - surgery; Oxidation resistance; Oxidation-Reduction; Oxidative stress; Oxidative Stress - physiology; Peroxidation; Peroxides; Prospective Studies; Research design; Sensitivity; Sphinganine; Sphingolipids; Sphingolipids - analysis; Sphingolipids - blood; Sphingolipids - metabolism; Sphingomyelin; Steatosis; Surgery; Transcription factors