Doxycycline mitigates corneal fibrosis by suppressing the focal adhesion pathway - Zhou, Jiaxin; He, Bingbing; Zou, Wenjin (Experimental eye research, 2025)
Keywords: Animals; Anti-Bacterial Agents - therapeutic use; Burns, Chemical - drug therapy; Burns, Chemical - metabolism; Burns, Chemical - pathology; Cornea - drug effects; Cornea - metabolism; Cornea - pathology; Corneal alkali burn; Corneal fibroblast; Disease Models, Animal; Doxycycline; Doxycycline - pharmacology; Doxycycline - therapeutic use; Eye Burns - chemically induced; Eye Burns - drug therapy; Eye Burns - metabolism; Eye Burns - pathology; Fibronectins - metabolism; Fibrosis - prevention & control; Focal adhesion pathway; Focal Adhesions - drug effects; Focal Adhesions - metabolism; Male; Ophthalmic Solutions; Rabbits; Signal Transduction - drug effects; Sodium Hydroxide - toxicity; Wound Healing - drug effects; Focal adhesion pathway; Corneal fibroblast; Corneal alkali burn; Doxycycline