In Vitro and In Silico Antistaphylococcal Activity of Indole Alkaloids Isolated from Tabernaemontana cymosa Jacq (Apocynaceae)

• Published in: Scientia pharmaceutica Vol. 90; no. 2; p. 38
• Main Authors: Pájaro-González, Yina, Cabrera-Barraza, Julián, Martelo-Ramírez, Geraldine, Oliveros-Díaz, Andrés F., Urrego-Álvarez, Juan, Quiñones-Fletcher, Wiston, Díaz-Castillo, Fredyc
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 14.06.2022
• Subjects: Bacteria; Chromatography; Ethanol; Gram-negative bacteria; methicillin-resistant S. aureus; monoterpene indol alkaloids; PBP2a; Seeds; voacangine; Colombia; United States > US; Germany

The species of the genus Tabernaemontana have a long tradition of use in different pathologies of infectious origins; the antibacterial, antifungal, and antiviral effects related to the control of the pathologies where the species of this genus are used, have been attributed to the indole monoterpen...