Inverse association between slow-wave sleep and low-grade inflammation in children and adolescents with major depressive disorder

• Published in: Sleep medicine Vol. 119; pp. 103 - 113
• Main Authors: Strumberger, Michael A., Häberling, Isabelle, Emery, Sophie, Albermann, Mona, Baumgartner, Noemi, Pedrett, Catrina, Wild, Salome, Contin-Waldvogel, Brigitte, Walitza, Susanne, Berger, Gregor, Schmeck, Klaus, Cajochen, Christian
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2024
• Subjects: Actigraphy; Adolescence; Adolescent; C-reactive protein; C-Reactive Protein - analysis; Child; Cross-Sectional Studies; Depression; Depressive Disorder, Major - blood; Depressive Disorder, Major - physiopathology; Electroencephalography; Female; Humans; Inflammation; Inflammation - blood; Male; Self Report; Severity of Illness Index; Sleep disturbance; Sleep Initiation and Maintenance Disorders - blood; Sleep Initiation and Maintenance Disorders - physiopathology; Sleep, Slow-Wave - physiology; Slow-wave sleep; Sleep disturbance; Adolescence; Depression; Inflammation; Slow-wave sleep; C-reactive protein

To investigate the relationship between both self-reported and objective sleep variables and low-grade inflammation in children and adolescents with major depressive disorder (MDD) of moderate to severe symptom severity. In this cross-sectional study, we examined twenty-nine children and adolescents...