The Gut Microbiome Is Associated with Clinical Response to Anti-PD-1/PD-L1 Immunotherapy in Gastrointestinal Cancer

• Published in: Cancer immunology research Vol. 8; no. 10; p. 1251
• Main Authors: Peng, Zhi, Cheng, Siyuan, Kou, Yan, Wang, Ziqi, Jin, Rong, Hu, Han, Zhang, Xiaotian, Gong, Ji-Fang, Li, Jian, Lu, Ming, Wang, Xicheng, Zhou, Jun, Lu, ZhiHao, Zhang, Quan, Tzeng, David T W, Bi, Dongtao, Tan, Yan, Shen, Lin
• Format: Journal Article
• Language: English
• Published: United States 01.10.2020

We report on a comprehensive analysis of the gut microbiomes of patients with gastrointestinal (GI) cancer receiving anti-PD-1/PD-L1 treatment. The human gut microbiota has been associated with clinical responses to anti-PD-1/PD-L1 immunotherapy in melanoma, non-small cell lung cancer, and renal cel...