Genetic absence of ALOX5 protects from homocysteine-induced memory impairment, tau phosphorylation and synaptic pathology - Li, Jian-Guo; Barrero, Carlos; Merali, Salim; Praticò, Domenico (Human molecular genetics, 2017)
Keywords: Animals; Arachidonate 5-Lipoxygenase - deficiency; Arachidonate 5-Lipoxygenase - genetics; Arachidonate 5-Lipoxygenase - metabolism; Brain - enzymology; Brain - metabolism; Disease Models, Animal; Female; Homocysteine - genetics; Homocysteine - metabolism; Humans; Male; Memory - physiology; Memory Disorders - metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurodegenerative Diseases - enzymology; Neurodegenerative Diseases - genetics; Neurodegenerative Diseases - metabolism; Phosphorylation; Synapses - metabolism