The Role of the TL1A/DR3 Axis in the Activation of Group 2 Innate Lymphoid Cells in Subjects with Eosinophilic Asthma

• Published in: American journal of respiratory and critical care medicine Vol. 202; no. 8; pp. 1105 - 1114
• Main Authors: Machida, Kentaro, Aw, Michael, Salter, Brittany M. A., Ju, Xiaotian, Mukherjee, Manali, Gauvreau, Gail M., O’Byrne, Paul M., Nair, Parameswaran, Sehmi, Roma
• Format: Journal Article
• Language: English
• Published: New York American Thoracic Society 15.10.2020
• Subjects: Allergens; Asthma; Cells; Cytokines

Machida et al discuss their study on the role of the TL1A/DR3 axis in the activation of group 2 innate lymphoid cells in subjects with eosinophilic asthma. The study involved subjects with mild asthma who were subject to allergen inhalation challenge, and DR3 expression on sputum cells was assessed....