Efficacy of Oral Itraconazole in the Treatment of Seborrheic Dermatitis in Vietnamese Adults Patients

This longitudinal study aims to evaluate the efficacy of oral itraconazole in the treatment of seborrheic dermatitis in Vietnamese patients. Thirty patients were enrolled at National Hospital of Dermatology and Venereology, Hanoi, Vietnam and were treated with oral itraconazole (200 mg daily in 14 d...

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Published inOpen access Macedonian journal of medical sciences Vol. 7; no. 2; pp. 224 - 226
Main Authors Van, Thuong Nguyen, Thi, Ngo Hoang, Van, Tam Hoang, Van, Hung Le, Huu, Nghi Dinh, Minh, Phuong Pham Thi, Cam, Van Tran, Huyen, My Le, Hau, Khang Tran, Gandolfi, Marco, Satolli, Francesca, Feliciani, Claudio, Tirant, Michael, Vojvodic, Aleksandra, Lotti, Torello
Format Journal Article
LanguageEnglish
Published Macedonia Republic of Macedonia 30.01.2019
Subjects
Clinical Science
Seborrheic dermatitis
Oral itraconazole
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Abstract This longitudinal study aims to evaluate the efficacy of oral itraconazole in the treatment of seborrheic dermatitis in Vietnamese patients. Thirty patients were enrolled at National Hospital of Dermatology and Venereology, Hanoi, Vietnam and were treated with oral itraconazole (200 mg daily in 14 days followed by 200 mg weekly in 4 weeks). The clinical severity was assessed by a four-parameter scoring system. All patients completed the six-week regimen with good adherence. At the week 2nd, 70% of the patients had moderate to severe diseases. At the week 6th, 63.4% of the patients achieve clearance of the lesions, and none had severe disease. No side effects were reported. Oral itraconazole can be an option for seborrheic dermatitis because of good efficacy, safety profile and adherence.
AbstractList This longitudinal study aims to evaluate the efficacy of oral itraconazole in the treatment of seborrheic dermatitis in Vietnamese patients. Thirty patients were enrolled at National Hospital of Dermatology and Venereology, Hanoi, Vietnam and were treated with oral itraconazole (200 mg daily in 14 days followed by 200 mg weekly in 4 weeks). The clinical severity was assessed by a four-parameter scoring system. All patients completed the six-week regimen with good adherence. At the week 2nd, 70% of the patients had moderate to severe diseases. At the week 6th, 63.4% of the patients achieve clearance of the lesions, and none had severe disease. No side effects were reported. Oral itraconazole can be an option for seborrheic dermatitis because of good efficacy, safety profile and adherence.
AIM: This longitudinal study aims to evaluate the efficacy of oral itraconazole in the treatment of seborrheic dermatitis in Vietnamese patients. METHODS: Thirty patients were enrolled at National Hospital of Dermatology and Venereology, Hanoi, Vietnam and were treated with oral itraconazole (200 mg daily in 14 days followed by 200 mg weekly in 4 weeks). The clinical severity was assessed by a four-parameter scoring system. All patients completed the six-week regimen with good adherence. RESULTS: At the week 2nd, 70% of the patients had moderate to severe diseases. At the week 6th, 63.4% of the patients achieve clearance of the lesions, and none had severe disease. No side effects were reported. CONCLUSION: Oral itraconazole can be an option for seborrheic dermatitis because of good efficacy, safety profile and adherence.
AIMThis longitudinal study aims to evaluate the efficacy of oral itraconazole in the treatment of seborrheic dermatitis in Vietnamese patients. METHODSThirty patients were enrolled at National Hospital of Dermatology and Venereology, Hanoi, Vietnam and were treated with oral itraconazole (200 mg daily in 14 days followed by 200 mg weekly in 4 weeks). The clinical severity was assessed by a four-parameter scoring system. All patients completed the six-week regimen with good adherence. RESULTSAt the week 2nd, 70% of the patients had moderate to severe diseases. At the week 6th, 63.4% of the patients achieve clearance of the lesions, and none had severe disease. No side effects were reported. CONCLUSIONOral itraconazole can be an option for seborrheic dermatitis because of good efficacy, safety profile and adherence.
Author Hau, Khang Tran
Cam, Van Tran
Satolli, Francesca
Thi, Ngo Hoang
Vojvodic, Aleksandra
Van, Hung Le
Tirant, Michael
Van, Thuong Nguyen
Van, Tam Hoang
Huyen, My Le
Huu, Nghi Dinh
Gandolfi, Marco
Feliciani, Claudio
Lotti, Torello
Minh, Phuong Pham Thi
AuthorAffiliation 4 University of Rome G. Marconi, Rome, Italy
6 Department of Dermatology and Venereology, Military Medical Academy of Belgrade, Belgrade, Serbia
2 Dermatology and Venerology Faculty, Hanoi Medical University, Hanoi, Vietnam
1 National Hospital of Dermatology and Venereology, Hanoi, Vietnam
5 Psoriasis Eczema Clinic, Melbourne, Australia
3 Unit of Dermatology, University of Parma, Parma, Italy
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Keywords Seborrheic dermatitis
Oral itraconazole
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AIM: This longitudinal study aims to evaluate the efficacy of oral itraconazole in the treatment of seborrheic dermatitis in Vietnamese patients. METHODS:...
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