Discrete multifunctional sequence-defined oligomers with controlled chirality

• Published in: Polymer chemistry Vol. 11; no. 24; pp. 44 - 446
• Main Authors: Li, Jie, Leclercq, Maxime, Fossepré, Mathieu, Surin, Mathieu, Glinel, Karine, Jonas, Alain M, Fernandes, Antony E
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 28.06.2020
• Subjects: Active control; Alkynes; Carboxylic acids; Chemical reactions; Chirality; Chloroformate; Cycloaddition; Dichroism; Drug delivery systems; Elongation; Imidazole; Information storage; NMR; Nuclear magnetic resonance; Oligomers; Peptides; Polymer chemistry; Self-assembly; Stereochemistry; Triazoles

Discrete sequence-defined oligomers are synthetic mimics of short peptides, with possible applications in catalysis, information storage, drug delivery or self-assembly. Here, we report on the efficient and stereocontrolled synthesis of sequence-defined poly(triazole-urethane) oligomers incorporatin...