Preparation of Thioflavones via Thiophosphoryl Chloride Mediated Cyclodehydration and Thionation of 1-(2-Hydroxyphenyl)-3-arylpropane-1,3-diones

A simple and convenient one-pot strategy for the preparation of thioflavones from 1,3-diketones is described. Cyclodehydration of a range of beta-diketones and thionation of the resulting flavones was achieved using thiophosphoryl chloride (PSCl3) which serves as both a catalyst and thionating agent...

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Published inSynthesis (Stuttgart) no. 1; pp. 30 - 32
Main Authors Vimal, Manorama, Pathak, Uma, Pandey, Lokesh Kumar, Suryanarayana, Malladi V. S.
Format Journal Article
LanguageEnglish
Published STUTTGART Thieme Medical Publishers 01.01.2011
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
flavones
4-THIOFLAVONES
thiophosphoryl chloride
DERIVATIVES
thioflavones
beta-diketones
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Abstract A simple and convenient one-pot strategy for the preparation of thioflavones from 1,3-diketones is described. Cyclodehydration of a range of beta-diketones and thionation of the resulting flavones was achieved using thiophosphoryl chloride (PSCl3) which serves as both a catalyst and thionating agent.
AbstractList A simple and convenient one-pot strategy for the preparation of thioflavones from 1,3-diketones is described. Cyclodehydration of a range of beta-diketones and thionation of the resulting flavones was achieved using thiophosphoryl chloride (PSCl3) which serves as both a catalyst and thionating agent.
Author Pathak, Uma
Pandey, Lokesh Kumar
Suryanarayana, Malladi V. S.
Vimal, Manorama
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10.1021/jo7022069
10.1039/b911844f
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Keywords flavones
4-THIOFLAVONES
thiophosphoryl chloride
DERIVATIVES
thioflavones
beta-diketones
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Snippet A simple and convenient one-pot strategy for the preparation of thioflavones from 1,3-diketones is described. Cyclodehydration of a range of beta-diketones and...
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Chemistry, Organic
Physical Sciences
Science & Technology
Title Preparation of Thioflavones via Thiophosphoryl Chloride Mediated Cyclodehydration and Thionation of 1-(2-Hydroxyphenyl)-3-arylpropane-1,3-diones
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