A metal-free visible-light-promoted phosphorylation/cyclization reaction in water towards 3-phosphorylated benzothiophenes

• Published in: ORGANIC CHEMISTRY FRONTIERS Vol. 7; no. 14; pp. 1884 - 1889
• Main Authors: Yuan, Xiao-Ya, Zeng, Fan-Lin, Zhu, Hu-Lin, Liu, Yan, Lv, Qi-Yan, Chen, Xiao-Lan, Peng, Lifen, Yu, Bing
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 21.07.2020; Royal Society of Chemistry
• Subjects: Chemistry; Chemistry, Organic; Functional groups; Light effects; Organic chemistry; Organic solvents; Phosphorylation; Physical Sciences; Room temperature; Science & Technology; Silver; QUINOLINE N-OXIDES; CATALYSIS; THIOLS; ACIDS; AMINES; INDUCED DEOXYGENATIVE C2-SULFONYLATION; EFFICIENT SYNTHESIS; C-H
• ISSN: 2052-4129; 2052-4110; 2052-4110
• DOI: 10.1039/d0qo00222d

A metal-free visible-light-induced 2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile (4CzIPN)-catalyzed phosphorylation/cyclization reaction was developed in water at room temperature for the synthesis of 3-phosphorylated benzothiophenes. Notably, the conventional organic solvents were avoided. More...