Impact of Rapid Weight Loss after Bariatric Surgery in Systemic Inflammatory Response and Pulmonary Hemodynamics in Severely Obese Subjects with Pulmonary Hypertension

• Published in: Journal of the American College of Surgeons Vol. 236; no. 2; pp. 365 - 372
• Main Authors: Valera, Roberto J, Fonnegra, Cristina Botero, Cogollo, Vicente J, Sarmiento-Cobos, Mauricio, Rivera, Carlos, Lo Menzo, Emanuele, Szomstein, Samuel, Rosenthal, Raul J
• Format: Journal Article
• Language: English
• Published: United States 01.02.2023
• Subjects: Bariatric Surgery; Hemodynamics; Humans; Hypertension, Pulmonary - complications; Inflammation; Obesity - complications; Obesity - surgery; Prospective Studies; Retrospective Studies; Systemic Inflammatory Response Syndrome - complications; Weight Loss

Pulmonary hypertension (PH) can be associated with obesity. The excessive production of proinflammatory mediators by dysfunctional adipocytes may enhance remodeling of the pulmonary vasculature and worsen pulmonary hemodynamics. This study aimed to describe the changes in pulmonary arterial pressure...