Myeloid sarcomas of the genitourinary tract: A multi-institutional study of sixteen tumors with review of literature

• Published in: Pathology, research and practice Vol. 272; p. 156106
• Main Authors: Shafi, Saba, Mohanty, Sambit K., Williamson, Sean R., Sharma, Shivani, Akgul, Mahmut, Sangoi, Ankur R., Arora, Samriti, Acosta, Andreas M., Panda, Soumya S., Mishra, Sourav K., Deshwal, Akansha, Jha, Shilpy, Mallik, Vipra, Lobo, Anandi, Dixit, Mallika, Kaushal, Seema, Quiroga-Garza, Gabriella, Cheng, Liang, Shana’ah, Arwa, Parwani, Anil V., Jaiswal, Ankita G., Dhillon, Jasreman, Biswas, Ghanshyam, Satturwar, Swati
• Format: Journal Article
• Language: English
• Published: Germany Elsevier GmbH 01.08.2025
• Subjects: Adolescent; Adult; Aged; Biomarkers, Tumor - analysis; Biomarkers, Tumor - genetics; Female; Flow cytometry; Genitourinary tract; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute - pathology; Male; Middle Aged; Myeloid sarcoma; Retrospective Studies; Sarcoma, Myeloid - genetics; Sarcoma, Myeloid - pathology; Urogenital Neoplasms - genetics; Urogenital Neoplasms - pathology; Young Adult; Immunohistochemistry; Flow cytometry; Myeloid sarcoma; Genitourinary tract

Myeloid sarcoma (MS) is a rare extramedullary manifestation of acute myelogenous leukemia (AML). Leukemic involvement of the genitourinary (GU) tract is extremely rare with only 2–7 % of the reported MS cases involving the kidney or urinary system. Patients with urinary tract MS can present with sig...