Genetic association of MIR-449B, GCLC, eNOS, SORD, and ENPP1 with diabetic retinopathy

• Published in: Experimental eye research Vol. 253; p. 110287
• Main Authors: Xu, Huijuan, Fan, Lin, Luo, Huaichao, Ju, Xueming, Li, Huan, Rong, Shisong, Yuan, Ye, Xiao, Jialing, Zhang, Ruifan, Wang, Kaifang, Zou, Rong, Hao, Fang, Shi, Yi, Zhou, Yu, Yang, Zhenglin, Liu, Yijun, Gong, Bo
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.04.2025
• Subjects: Aged; Case-Control Studies; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - genetics; Diabetic retinopathy; Diabetic Retinopathy - genetics; Diabetic Retinopathy - metabolism; Female; Funnel plots; Genetic Predisposition to Disease; Genotype; Humans; Male; Meta-analysis; MicroRNAs - genetics; Middle Aged; Nitric Oxide Synthase Type III - genetics; Nitric Oxide Synthase Type III - metabolism; Phosphoric Diester Hydrolases - genetics; Phosphoric Diester Hydrolases - metabolism; Polymorphism, Single Nucleotide; Pyrophosphatases; Single nucleotide polymorphism; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Type 2 diabetes mellitus; Diabetic retinopathy; Single nucleotide polymorphism; Type 2 diabetes mellitus; Funnel plots; Meta-analysis

Identifying the genetic risk factors of diabetic retinopathy (DR) is essential for discovering the potential pathogenesis of DR. This study determined the association of DR with five single nucleotide polymorphisms (SNPs) specifically in type 2 diabetes mellitus (T2DM) patients, including rs10061133...