Near-infrared pH-sensitive probes based on aza-Nile Blue for detecting interactions between mitochondria and lysosomes

• Published in: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Vol. 338; p. 126169
• Main Authors: Wang, Hui, Xu, Xu, Ni, Wen-Pei, Sun, Ru, Zhang, Yi, Ge, Jian-Feng
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 05.10.2025
• Subjects: Aza Compounds - chemistry; Aza−Nile Blue; Dual organelle−targeting; Fluorescent Dyes - chemistry; HeLa Cells; Humans; Hydrogen-Ion Concentration; Lysosomes - metabolism; Mitochondria - metabolism; Mitochondria−migrating; Mitophagy; Oxazines - chemistry; pH sensitive; Spectrometry, Fluorescence; Spectroscopy, Near-Infrared - methods; pH sensitive; Mitochondria−migrating; Dual organelle−targeting; Aza−Nile Blue; Mitophagy

Near-infrared pH-sensitive probes based on aza-Nile Blue for detecting interactions between mitochondria and lysosomes. [Display omitted] •Water soluble and high molar extinction coefficient.•Linear response ranges of 4 pH units around 8.0.•Visualization of mitochondrial and lysosomal dynamic intera...