In vitro Anti-Cancer Activity of Rosuvastatin and Ketorolac Nanoformulations against DDX3

• Published in: Journal of young pharmacists Vol. 9; no. 4; pp. 537 - 544
• Main Authors: Bheemanapally, Khaggeswar, Thimmaraju, Manish Kumar, Kasagoni, Sagar, Thatikonda, Prathyusha, Akula, Swathi, Kodamala, Kranthi Raj, Kakarla, Lavanya, Gummadi, Sridhar Babu, Nemani, Harishankar, Botlagunta, Mahendran
• Format: Journal Article
• Language: English
• Published: Bangalore InPharm 01.10.2017
• Subjects: Bioavailability; Cancer; Leukemia; Nanoemulsions

Background: DDX3 is the human RNA helicase and enhanced expression of DDX3 protein was found in several cancers including leukemia. Statin family of drugs shown to inhibit the growth of acute myeloid leukemia cells. Objective: In this paper we report the molecular interaction of Rosuvastatin Calcium...