Dihydroxyphenylglycol as a Biomarker of Norepinephrine Transporter Inhibition by Atomoxetine: Human Model to Assess Central and Peripheral Effects of Dosing - Bieck, Peter R; Leibowitz, Mark; Lachno, D Richard; Ledent, Edouard; Padich, Robert; Jhee, Stan (Journal of clinical psychopharmacology, 2016)
Keywords: Adrenergic Uptake Inhibitors - administration & dosage; Adrenergic Uptake Inhibitors - pharmacokinetics; Adrenergic Uptake Inhibitors - pharmacology; Adult; Area Under Curve; Atomoxetine Hydrochloride - administration & dosage; Atomoxetine Hydrochloride - pharmacokinetics; Atomoxetine Hydrochloride - pharmacology; Biomarkers - blood; Biomarkers - cerebrospinal fluid; Brain-Derived Neurotrophic Factor - cerebrospinal fluid; Female; Humans; Male; Methoxyhydroxyphenylglycol - analogs & derivatives; Methoxyhydroxyphenylglycol - blood; Methoxyhydroxyphenylglycol - cerebrospinal fluid; Middle Aged; Norepinephrine - metabolism; Norepinephrine Plasma Membrane Transport Proteins - antagonists & inhibitors; Norepinephrine Plasma Membrane Transport Proteins - metabolism; Young Adult