Pulcherrimins A – D, novel diterpene dibenzoates from Caesalpinia pulcherrima with selective activity against DNA repair-deficient yeast mutants

• Published in: Tetrahedron Vol. 53; no. 5; pp. 1583 - 1592
• Main Authors: Patil, Ashok D., Freyer, Alan J., Lee Webb, R., Zuber, Gary, Reichwein, Rex, Bean, Mark F., Faucette, Leo, Johnson, Randall K.
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 03.02.1997; Elsevier
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology

Bioassay-guided fractionation of the MeOH/CH 2Cl 2 extract of the roots of Caesalpinia pulcherrima yielded four novel dibenzoate diterpenes, pulcherrimins A, B, C and D (1–4). The structures of these compounds including their absolute configuration were established by interpretation of spectral data...