Role of Polyvinylpyrrolidone in Dissolving Microneedle for Efficient Transdermal Drug Delivery: In vitro and Clinical Studies

• Published in: Bulletin of the Korean Chemical Society Vol. 39; no. 6; pp. 789 - 793
• Main Authors: Shim, Woo Sun, Hwang, Young Min, Park, Sun Gyoo, Lee, Cheon Koo, Kang, Nae Gyu
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley‐VCH Verlag GmbH & Co. KGaA 01.06.2018; 대한화학회
• Subjects: Anti‐wrinkle; Dissolving microneedle; Micromolding; Transdermal drug delivery; 화학

The purpose of this study is to find an optimum composition of microneedles that penetrate the skin and rapidly dissolve within the cutaneous layer in a few minutes. A micromolding method was introduced to prepare drug‐loaded dissolving microneedles by using biocompatible, water‐soluble polymers suc...