Influence of the dipeptide linker configuration on the activity of PSMA ligands
[Display omitted] Selective ligands of an urea-based prostate specific membrane antigen with a phenylalanine/tyrosine-based dipeptide linker and with a mingled chiral centers configuration and/or substituted aromatic fragments were prepared in seven steps by liquid- and in six steps by solid-phase s...
Saved in:
| Published in | Mendeleev communications Vol. 30; no. 6; pp. 756 - 759 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Elsevier B.V
01.11.2020
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0959-9436 |
| DOI | 10.1016/j.mencom.2020.11.022 |
Cover
Loading…
| Abstract | [Display omitted]
Selective ligands of an urea-based prostate specific membrane antigen with a phenylalanine/tyrosine-based dipeptide linker and with a mingled chiral centers configuration and/or substituted aromatic fragments were prepared in seven steps by liquid- and in six steps by solid-phase synthesis. In vitro test for inhibiting the cleavage of N-acetylaspartylglutamate revealed the optimum linker containing l-phenylalanine in the structure on the N-terminus of a dipeptide chain. |
|---|---|
| AbstractList | [Display omitted]
Selective ligands of an urea-based prostate specific membrane antigen with a phenylalanine/tyrosine-based dipeptide linker and with a mingled chiral centers configuration and/or substituted aromatic fragments were prepared in seven steps by liquid- and in six steps by solid-phase synthesis. In vitro test for inhibiting the cleavage of N-acetylaspartylglutamate revealed the optimum linker containing l-phenylalanine in the structure on the N-terminus of a dipeptide chain. |
| Author | Petrov, Stanislav A. Uspenskaya, Anastasiya A. Skvortsov, Dmitry A. Beloglazkina, Elena K. Majouga, Alexander G. Nimenko, Ekaterina A. Machulkin, Alexey E. Shafikov, Radik R. |
| Author_xml | – sequence: 1 givenname: Anastasiya A. surname: Uspenskaya fullname: Uspenskaya, Anastasiya A. email: Uspenskaya.n@gmail.com organization: Department of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation – sequence: 2 givenname: Alexey E. surname: Machulkin fullname: Machulkin, Alexey E. organization: Department of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation – sequence: 3 givenname: Ekaterina A. surname: Nimenko fullname: Nimenko, Ekaterina A. organization: Department of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation – sequence: 4 givenname: Radik R. surname: Shafikov fullname: Shafikov, Radik R. organization: A. N. Belozersky Institute of Physico-Chemical Biology, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation – sequence: 5 givenname: Stanislav A. surname: Petrov fullname: Petrov, Stanislav A. organization: Department of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation – sequence: 6 givenname: Dmitry A. surname: Skvortsov fullname: Skvortsov, Dmitry A. organization: A. N. Belozersky Institute of Physico-Chemical Biology, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation – sequence: 7 givenname: Elena K. surname: Beloglazkina fullname: Beloglazkina, Elena K. organization: Department of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation – sequence: 8 givenname: Alexander G. surname: Majouga fullname: Majouga, Alexander G. organization: Department of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation |
| BookMark | eNqFkE1LAzEQhnOoYFv9Bx72D-yar93tehBK8aNQqaCeQzaZ1NRtUrJpwX9v1nryoDAwMLzPMPNM0Mh5BwhdEVwQTKrrbbEDp_yuoJimESkwpSM0xk3Z5A1n1Tma9P0WY1yXjIzReulMd0gEZN5k8R0ybfewj1ZD1ln3ASFT3hm7OQQZrXdZqiElVbRHGz8H6vnlaZ7CG-l0f4HOjOx6uPzpU_R2f_e6eMxX64flYr7KFcNVzAHqSmmlOWkrTTirmWSGYjUzhjBeSq5o3UArSyCkpA2lFPOGY16V6ey2nbEpujntVcH3fQAjlI3fF8YgbScIFoMOsRUnHWLQIQgRSUeC-S94H-xOhs__sNsTBumxo4UgemUHddoGUFFob_9e8AUQgYAS |
| CitedBy_id | crossref_primary_10_3390_ijms241512206 crossref_primary_10_1021_acsomega_4c10142 crossref_primary_10_1134_S1070428024080013 crossref_primary_10_1016_j_bmcl_2022_128840 crossref_primary_10_1016_j_mencom_2023_06_010 crossref_primary_10_1016_j_molstruc_2021_130127 crossref_primary_10_31857_S0514749224020058 crossref_primary_10_3390_ijms241411327 |
| Cites_doi | 10.3109/1061186X.2016.1154564 10.1111/j.1399-3011.1978.tb02896.x 10.1111/j.1399-3011.1991.tb00769.x 10.1248/cpb.42.724 10.1021/jm100729b 10.1021/ol048771l 10.1016/j.apradiso.2011.03.041 10.1021/cr980040+ 10.1007/s11094-019-01994-1 10.1016/j.bmcl.2019.01.040 10.1016/S0040-4039(00)99113-5 10.1016/j.bmcl.2019.06.035 10.1002/cmdc.200500044 10.1002/cbin.10055 10.2174/092986712799034888 10.1021/mp9000712 10.3322/caac.21551 |
| ContentType | Journal Article |
| Copyright | 2020 |
| Copyright_xml | – notice: 2020 |
| DBID | AAYXX CITATION |
| DOI | 10.1016/j.mencom.2020.11.022 |
| DatabaseName | CrossRef |
| DatabaseTitle | CrossRef |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Chemistry |
| EndPage | 759 |
| ExternalDocumentID | 10_1016_j_mencom_2020_11_022 S0959943620303047 |
| GroupedDBID | --K --M .~1 0R~ 123 1B1 1RT 1~. 1~5 29M 4.4 457 4G. 5VS 7-5 71M 8P~ 9JN AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AARLI AAXUO ABJNI ABMAC ABXDB ABYKQ ACDAQ ACGFO ACGFS ACNNM ACRLP ADBBV ADECG ADEZE ADMUD AEBSH AEKER AENEX AFKWA AFTJW AFZHZ AGHFR AGUBO AGYEJ AHHHB AIEXJ AIKHN AITUG AJBFU AJOXV AJSZI ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC CAG COF CS3 DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 FDB FEDTE FGOYB FIRID FLBIZ FNPLU FYGXN GBLVA HMS HVGLF HZ~ IHE J1W KOM M2Y M41 MO0 N9A O-L O9- OAUVE OZT P-8 P-9 P2P PC. Q38 R2- R56 RIG ROL RPZ SCB SDF SDG SES SLH SOC SPC SPCBC SSK SSZ T5K ~G- AAXKI AAYWO AAYXX ABWVN ACRPL ADNMO AEIPS AGCQF AGQPQ AKRWK ANKPU APXCP CITATION |
| ID | FETCH-LOGICAL-c306t-ee76cdcd41b6d14373a3f20c8ff1345a4c279eba5e1152922204940465753bb83 |
| IEDL.DBID | .~1 |
| ISSN | 0959-9436 |
| IngestDate | Thu Jul 03 08:37:22 EDT 2025 Thu Apr 24 22:56:16 EDT 2025 Fri Feb 23 02:48:07 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | target drug delivery prostate cancer amides prostate specific membrane antigen solid-phase synthesis peptide synthesis |
| Language | English |
| License | https://www.elsevier.com/tdm/userlicense/1.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c306t-ee76cdcd41b6d14373a3f20c8ff1345a4c279eba5e1152922204940465753bb83 |
| PageCount | 4 |
| ParticipantIDs | crossref_citationtrail_10_1016_j_mencom_2020_11_022 crossref_primary_10_1016_j_mencom_2020_11_022 elsevier_sciencedirect_doi_10_1016_j_mencom_2020_11_022 |
| PublicationCentury | 2000 |
| PublicationDate | November-December 2020 2020-11-00 |
| PublicationDateYYYYMMDD | 2020-11-01 |
| PublicationDate_xml | – month: 11 year: 2020 text: November-December 2020 |
| PublicationDecade | 2020 |
| PublicationTitle | Mendeleev communications |
| PublicationYear | 2020 |
| Publisher | Elsevier B.V |
| Publisher_xml | – name: Elsevier B.V |
| References | A. Machulkin, A. Uspenskaya, A. Ber, S. Petrov, I. Saltykova, Y. Ivanenkov, D. Skvortsov, A. Erofeev, P. Gorelkin, E. Beloglazkina, E. Belov, E. Khazanova and A. Mazhuga, Patent RU 2697519C1, 2019. Shendage, Fröhlich, Haufe (bib0070) 2004; 6 Shin, Lee (bib0075) 2009 Uspenskaya, Machulkin, Mazhuga, Beloglazkina (bib0015) 2019; 53 Machulkin, Ivanenkov, Aladinskaya, Veselov, Aladinskiy, Beloglazkina, Koteliansky, Shakhbazyan, Sandulenko, Majouga (bib0030) 2016; 24 Jayaprakash, Wang, Heston, Kozikowski (bib0035) 2006; 1 Chekhonin, Gerigor’ev, Zhirkov, Lebedev (bib0010) 2002; 48 Kularatne, Venkatesh, Santhapuram, Wang, Vaitilingam, Henne, Low (bib0045) 2010; 53 Ben Jemaa, Sallami, Céraline, Oueslati (bib0120) 2013; 37 Ivanenkov, Machulkin, Garanina, Skvortsov, Uspenskaya, Deyneka, Trofimenko, Beloglazkina, Zyk, Koteliansky, Bezrukov, Aladinskaya, Vorobyeva, Puchinina, Riabykh, Sofronova, Malyshev, Majouga (bib0025) 2019; 29 Lundt, Johansen, Vølund, Markussen (bib0065) 1978; 12 Barinka, Rojas, Slusher, Pomper (bib0020) 2012; 19 Machulkin, Skvortsov, Ivanenkov, Ber, Kavalchuk, Aladinskaya, Uspenskaya, Shafikov, Plotnikova, Yakubovskaya, Nimenko, Zyk, Beloglazkina, Zyk, Koteliansky, Majouga (bib0040) 2019; 29 Horoszewicz, Leong, Kawinski, Karr, Rosenthal, Chu, Mirand, Murphy (bib0115) 1983; 43 Fujiwara, Akaji, Yoshiaki (bib0110) 1994; 42 (bib0090) 2005 Malik, Machulla, Solbach, Winter, Reske, Zlatopolskiy (bib0050) 2011; 69 Kularatne, Zhou, Yang, Post, Low (bib0055) 2009; 6 Siegel, Miller, Jemal (bib0005) 2019; 69 (bib0095) 1995 Guillier, Orain, Bradley (bib0100) 2000; 100 Pearson, Blanchette, Baker, Guindon (bib0085) 1989; 30 Lygo, Pelletier (bib0080) 2013 Chatzi, Barlos, Gatos, Stavropoulos (bib0105) 1991; 37 Malik (10.1016/j.mencom.2020.11.022_bib0050) 2011; 69 Siegel (10.1016/j.mencom.2020.11.022_bib0005) 2019; 69 Ivanenkov (10.1016/j.mencom.2020.11.022_bib0025) 2019; 29 Shendage (10.1016/j.mencom.2020.11.022_bib0070) 2004; 6 Uspenskaya (10.1016/j.mencom.2020.11.022_bib0015) 2019; 53 Machulkin (10.1016/j.mencom.2020.11.022_bib0030) 2016; 24 Guillier (10.1016/j.mencom.2020.11.022_bib0100) 2000; 100 Lygo (10.1016/j.mencom.2020.11.022_bib0080) 2013 10.1016/j.mencom.2020.11.022_bib0060 Machulkin (10.1016/j.mencom.2020.11.022_bib0040) 2019; 29 Horoszewicz (10.1016/j.mencom.2020.11.022_bib0115) 1983; 43 Fujiwara (10.1016/j.mencom.2020.11.022_bib0110) 1994; 42 (10.1016/j.mencom.2020.11.022_bib0090) 2005 Chekhonin (10.1016/j.mencom.2020.11.022_bib0010) 2002; 48 Kularatne (10.1016/j.mencom.2020.11.022_bib0045) 2010; 53 Chatzi (10.1016/j.mencom.2020.11.022_bib0105) 1991; 37 Barinka (10.1016/j.mencom.2020.11.022_bib0020) 2012; 19 Ben Jemaa (10.1016/j.mencom.2020.11.022_bib0120) 2013; 37 Jayaprakash (10.1016/j.mencom.2020.11.022_bib0035) 2006; 1 Kularatne (10.1016/j.mencom.2020.11.022_bib0055) 2009; 6 (10.1016/j.mencom.2020.11.022_bib0095) 1995 Shin (10.1016/j.mencom.2020.11.022_bib0075) 2009 Pearson (10.1016/j.mencom.2020.11.022_bib0085) 1989; 30 Lundt (10.1016/j.mencom.2020.11.022_bib0065) 1978; 12 |
| References_xml | – year: 2005 ident: bib0090 publication-title: Peptide Synthesis and Applications – reference: A. Machulkin, A. Uspenskaya, A. Ber, S. Petrov, I. Saltykova, Y. Ivanenkov, D. Skvortsov, A. Erofeev, P. Gorelkin, E. Beloglazkina, E. Belov, E. Khazanova and A. Mazhuga, Patent RU 2697519C1, 2019. – volume: 37 start-page: 464 year: 2013 ident: bib0120 publication-title: Cell Biol. Int. – volume: 1 start-page: 299 year: 2006 ident: bib0035 publication-title: ChemMedChem – volume: 30 start-page: 2739 year: 1989 ident: bib0085 publication-title: Tetrahedron Lett. – volume: 43 start-page: 1809 year: 1983 ident: bib0115 publication-title: Cancer Res. – volume: 19 start-page: 856 year: 2012 ident: bib0020 publication-title: Curr. Med. Chem. – volume: 69 start-page: 7 year: 2019 ident: bib0005 publication-title: Ca-Cancer J. Clin. – volume: 37 start-page: 513 year: 1991 ident: bib0105 publication-title: Int. J. Pept. Protein Res. – volume: 42 start-page: 724 year: 1994 ident: bib0110 publication-title: Chem. Pharm. Bull. – volume: 100 start-page: 2091 year: 2000 ident: bib0100 publication-title: Chem. Rev. – volume: 53 start-page: 288 year: 2019 ident: bib0015 publication-title: Pharm. Chem. J. – volume: 12 start-page: 258 year: 1978 ident: bib0065 publication-title: Int. J. Pept. Protein Res. – volume: 24 start-page: 679 year: 2016 ident: bib0030 publication-title: J. Drug Target. – volume: 29 start-page: 2229 year: 2019 ident: bib0040 publication-title: Bioorg. Med. Chem. Lett. – volume: 6 start-page: 3675 year: 2004 ident: bib0070 publication-title: Org. Lett. – start-page: 3307 year: 2009 ident: bib0075 publication-title: Synlett – year: 1995 ident: bib0095 publication-title: Peptide Synthesis Protocols – volume: 69 start-page: 1014 year: 2011 ident: bib0050 publication-title: Appl. Radiat. Isot. – volume: 53 start-page: 7767 year: 2010 ident: bib0045 publication-title: J. Med. Chem. – year: 2013 ident: bib0080 article-title: 1-Hydroxybenzotriazole – volume: 48 start-page: 31 year: 2002 ident: bib0010 publication-title: Voprosy Med. Khim. – volume: 6 start-page: 790 year: 2009 ident: bib0055 publication-title: Mol. Pharm. – volume: 29 start-page: 1246 year: 2019 ident: bib0025 publication-title: Bioorg. Med. Chem. Lett. – ident: 10.1016/j.mencom.2020.11.022_bib0060 – volume: 43 start-page: 1809 year: 1983 ident: 10.1016/j.mencom.2020.11.022_bib0115 publication-title: Cancer Res. – volume: 24 start-page: 679 year: 2016 ident: 10.1016/j.mencom.2020.11.022_bib0030 publication-title: J. Drug Target. doi: 10.3109/1061186X.2016.1154564 – volume: 12 start-page: 258 year: 1978 ident: 10.1016/j.mencom.2020.11.022_bib0065 publication-title: Int. J. Pept. Protein Res. doi: 10.1111/j.1399-3011.1978.tb02896.x – volume: 37 start-page: 513 year: 1991 ident: 10.1016/j.mencom.2020.11.022_bib0105 publication-title: Int. J. Pept. Protein Res. doi: 10.1111/j.1399-3011.1991.tb00769.x – volume: 42 start-page: 724 year: 1994 ident: 10.1016/j.mencom.2020.11.022_bib0110 publication-title: Chem. Pharm. Bull. doi: 10.1248/cpb.42.724 – year: 2013 ident: 10.1016/j.mencom.2020.11.022_bib0080 – volume: 53 start-page: 7767 year: 2010 ident: 10.1016/j.mencom.2020.11.022_bib0045 publication-title: J. Med. Chem. doi: 10.1021/jm100729b – volume: 6 start-page: 3675 year: 2004 ident: 10.1016/j.mencom.2020.11.022_bib0070 publication-title: Org. Lett. doi: 10.1021/ol048771l – year: 1995 ident: 10.1016/j.mencom.2020.11.022_bib0095 – volume: 69 start-page: 1014 year: 2011 ident: 10.1016/j.mencom.2020.11.022_bib0050 publication-title: Appl. Radiat. Isot. doi: 10.1016/j.apradiso.2011.03.041 – start-page: 3307 year: 2009 ident: 10.1016/j.mencom.2020.11.022_bib0075 publication-title: Synlett – volume: 100 start-page: 2091 year: 2000 ident: 10.1016/j.mencom.2020.11.022_bib0100 publication-title: Chem. Rev. doi: 10.1021/cr980040+ – volume: 53 start-page: 288 year: 2019 ident: 10.1016/j.mencom.2020.11.022_bib0015 publication-title: Pharm. Chem. J. doi: 10.1007/s11094-019-01994-1 – volume: 29 start-page: 1246 year: 2019 ident: 10.1016/j.mencom.2020.11.022_bib0025 publication-title: Bioorg. Med. Chem. Lett. doi: 10.1016/j.bmcl.2019.01.040 – volume: 30 start-page: 2739 year: 1989 ident: 10.1016/j.mencom.2020.11.022_bib0085 publication-title: Tetrahedron Lett. doi: 10.1016/S0040-4039(00)99113-5 – volume: 29 start-page: 2229 year: 2019 ident: 10.1016/j.mencom.2020.11.022_bib0040 publication-title: Bioorg. Med. Chem. Lett. doi: 10.1016/j.bmcl.2019.06.035 – volume: 1 start-page: 299 year: 2006 ident: 10.1016/j.mencom.2020.11.022_bib0035 publication-title: ChemMedChem doi: 10.1002/cmdc.200500044 – volume: 48 start-page: 31 year: 2002 ident: 10.1016/j.mencom.2020.11.022_bib0010 publication-title: Voprosy Med. Khim. – year: 2005 ident: 10.1016/j.mencom.2020.11.022_bib0090 – volume: 37 start-page: 464 year: 2013 ident: 10.1016/j.mencom.2020.11.022_bib0120 publication-title: Cell Biol. Int. doi: 10.1002/cbin.10055 – volume: 19 start-page: 856 year: 2012 ident: 10.1016/j.mencom.2020.11.022_bib0020 publication-title: Curr. Med. Chem. doi: 10.2174/092986712799034888 – volume: 6 start-page: 790 year: 2009 ident: 10.1016/j.mencom.2020.11.022_bib0055 publication-title: Mol. Pharm. doi: 10.1021/mp9000712 – volume: 69 start-page: 7 year: 2019 ident: 10.1016/j.mencom.2020.11.022_bib0005 publication-title: Ca-Cancer J. Clin. doi: 10.3322/caac.21551 |
| SSID | ssj0007531 |
| Score | 2.2470095 |
| Snippet | [Display omitted]
Selective ligands of an urea-based prostate specific membrane antigen with a phenylalanine/tyrosine-based dipeptide linker and with a mingled... |
| SourceID | crossref elsevier |
| SourceType | Enrichment Source Index Database Publisher |
| StartPage | 756 |
| SubjectTerms | amides peptide synthesis prostate cancer prostate specific membrane antigen solid-phase synthesis target drug delivery |
| Title | Influence of the dipeptide linker configuration on the activity of PSMA ligands |
| URI | https://dx.doi.org/10.1016/j.mencom.2020.11.022 |
| Volume | 30 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LS8NAEF5KL3oRn1hf7MHrtnlsssmxFEsVqkIt9Baym9kS0baU9upvdyab-ABREHJJmIEwmUy-zc73DWPXRYx5YyAWKlcgpFRSpCkQ2T1HQGED31TyxeP7eDSVd7No1mKDhgtDbZV17Xc1varW9ZVeHc3eqix7E_qDlUoswJintHlEDHapqK2v-_bZ5oFw3Hd6e6kg64Y-V_V4vZJYJPHRA6odXS8Ifv48ffnkDPfZXo0Ved_dzgFrweKQ7QyaEW1H7OG2GTHCl5YjlONFuaI2lQI47czCmuNy15bzrXvOHA-yIjIDzYwgr8fJuI_Gc6L8HrPp8OZpMBL1hARhEOpvBICKTWEK6eu48EmlKA9t4JnEWj-UUS5NoFLQeQQI_IIUsQDJweCSGEFaqHUSnrD2YrmAU8YjqW3qJaANgpRY5TmExosgiTW-8YgjOixsApOZWj6cpli8ZE2f2HPmwplROHFlkWE4O0x8eK2cfMYf9qqJefYtDTKs8L96nv3b85zt0pkjGF6w9ma9hUtEGht9VaXSO5P4z-4 |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La8JAEB6sPdhL6ZPa5x56Xc1j8zqKVLRVW1DB25LdbMTSqohe-9s7k0cfUFoo5JTMQJjMzn6TnW8G4Dbx0W-08XkQB4YLEQgeRYbI7jECitSxdda-eDD0uxNxP_WmFWiXXBgqqyxifx7Ts2hd3GkW1myu5vPmiP5gRQIDMPopHR7twK7A5UvzGxpvn3UeiMftvOFexEm85M9lRV6v1C2SCOkOBY-G5Tg_709f9pzOAewXYJG18vc5hIpZHEGtXc5oO4bHXjljhC1ThliOJfMV1akkhtHRrFkzzHfT-Wybf2iGF0kRm4GGRpDW02jQQuEZcX5PYNK5G7e7vBiRwDVi_Q03JvB1ohNhKz-xqU1R7KaOpcM0tV3hxUI7QWRU7BlEfk6EYID6wWBOjCjNVSp0T6G6WC7MGTBPqDSyQqM0ohQ_iGPjasszoa9wySOQqINbGkbqon84jbF4kWWh2LPMzSnJnJhaSDRnHfiH1irvn_GHfFDaXH7zA4kh_lfN839r3kCtOx70Zb83fLiAPXqSsw0vobpZb80Vwo6Nus7c6h0MddMJ |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Influence+of+the+dipeptide+linker+configuration+on+the+activity+of+PSMA+ligands&rft.jtitle=Mendeleev+communications&rft.au=Uspenskaya%2C+Anastasiya+A.&rft.au=Machulkin%2C+Alexey+E.&rft.au=Nimenko%2C+Ekaterina+A.&rft.au=Shafikov%2C+Radik+R.&rft.date=2020-11-01&rft.issn=0959-9436&rft.volume=30&rft.issue=6&rft.spage=756&rft.epage=759&rft_id=info:doi/10.1016%2Fj.mencom.2020.11.022&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_mencom_2020_11_022 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0959-9436&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0959-9436&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0959-9436&client=summon |