A comparison of isosorbide mononitrate and misoprostol cervical ripening before suction evacuation

• Published in: Obstetrics and gynecology (New York. 1953) Vol. 102; no. 3; pp. 583 - 588
• Main Authors: Ivy Li, C.F, Carina Chan, C.W, Ho, P.C
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.09.2003; Elsevier Science
• Subjects: Abortion, Induced - methods; Adolescent; Adult; Analysis of Variance; Biological and medical sciences; Cervical Ripening - drug effects; Double-Blind Method; Female; Genital system. Reproduction; Humans; Isosorbide Dinitrate - analogs & derivatives; Isosorbide Dinitrate - therapeutic use; Medical sciences; Middle Aged; Misoprostol - therapeutic use; Pharmacology. Drug treatments; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Probability; Sensitivity and Specificity; Statistics, Nonparametric; Vacuum Curettage - methods; Antianginal agent; Suction; Coronary vasodilator agent; Prostaglandin E1; Antiulcer agent; Uterine cervix; Misoprostol; Randomization; Antisecretory agent; Organic nitrate; Female; Human; Aspiration; Induced abortion; Isosorbide mononitrate; Controlled therapeutic trial; Oxytocic; Antiarrhythmic agent; Ripening; Donor; Analog; Nitric oxide; Evacuation; Double blind study; Preoperative; Comparative study; Prostaglandin derivatives

To compare the efficacy of a nitric oxide donor (isosorbide mononitrate) and a prostaglandin E1 analogue (misoprostol) for cervical priming before suction termination of pregnancy. This was a randomized, double blind, placebo-controlled trial. One hundred twenty-six healthy women requesting terminat...