Synthesis of N-methoxy-1‑phosphoryloxy imidates through a copper-catalyzed cross-dehydrogenative coupling of N-methoxylamides with phosphites

• Published in: Tetrahedron letters Vol. 105; pp. 154049 - 154053
• Main Authors: Deng, Xiangmeng, Wang, Ying, Liu, Jin-Biao, Wan, Changfeng, Luo, Nianhua
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 31.08.2022; Elsevier
• Subjects: Chemistry; Chemistry, Organic; Copper catalysis; Cross-dehydrogenative coupling; N-methoxylamide; Phosphite; Physical Sciences; Science & Technology; N-methoxylamide; Cross-dehydrogenative coupling; Copper catalysis; Phosphite; PROTOCOL; H-PHOSPHONATES; GENERAL-METHOD; ALCOHOLS; P-O; AMINES; ESTERS; OXIDES; EFFICIENT; AMIDES

[Display omitted] Phosphonates are important organic compounds, which are widely used in medicine, materials, agriculture and catalysis. In this paper, we report a copper-catalyzed cross-dehydrogenative coupling of N-methoxamides with various phosphites to synthesize a series of N-methoxy-1‑phosphor...