Sarcomatoid carcinoma of the urinary bladder: the final common pathway of urothelial carcinoma dedifferentiation

• Published in: The American journal of surgical pathology Vol. 35; no. 5; p. e34
• Main Authors: Cheng, Liang, Zhang, Shaobo, Alexander, Riley, Maclennan, Gregory T, Hodges, Kurt B, Harrison, Beth T, Lopez-Beltran, Antonio, Montironi, Rodolfo
• Format: Journal Article
• Language: English
• Published: United States 01.05.2011
• Subjects: Carcinoma - classification; Carcinoma - genetics; Carcinoma - pathology; Carcinoma, Transitional Cell - classification; Carcinoma, Transitional Cell - genetics; Carcinoma, Transitional Cell - pathology; Diagnosis, Differential; Humans; Urinary Bladder Neoplasms - classification; Urinary Bladder Neoplasms - genetics; Urinary Bladder Neoplasms - pathology

Sarcomatoid carcinoma of the urinary bladder is an unusual malignancy composed of both carcinomatous and sarcomatous components. It is an aggressive tumor that presents at an advanced stage and confers a much poorer prognosis than conventional urothelial carcinoma. The proper nomenclature and histog...