A concise and efficient synthesis of tetrahydroquinoline alkaloids using the phase transfer mediated Wittig olefination reaction

[Display omitted] •The total synthesis of 1,2,3,4-tetrahydroquinoline alkaloids, was carry out in three steps and high yields.•The key step of this approach is based on an unusual Wittig reaction by using the phase transfer medium.•This protocol is compatible with chiral aldehydes. The present study...

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Published inTetrahedron letters Vol. 58; no. 33; pp. 3311 - 3315
Main Authors Diaz-Muñoz, Gaspar, Isidorio, Raquel Geralda, Miranda, Izabel Luzia, de Souza Dias, Gabriel Nunes, Diaz, Marisa Alves Nogueira
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 16.08.2017
Elsevier
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