Preparation of linearly fused 6-6-5 and 6-5-5 carbotricyclic ring systems related to the natural polyquinanes
A short pathway to the formation of the title framework is elaborated via (i) the tandem addition of arylsulfenium chloride and 1-siloxycycloalkenes across the double bond of dicobalthexacarbonyl complex of vinylacetylene, (ii) the diastereoselective Grignard reaction at the carbonyl group of the fo...
Saved in:
Published in | Mendeleev communications Vol. 18; no. 4; pp. 203 - 204 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier B.V
01.07.2008
|
Online Access | Get full text |
Cover
Loading…
Summary: | A short pathway to the formation of the title framework is elaborated
via (i) the tandem addition of arylsulfenium chloride and 1-siloxycycloalkenes across the double bond of dicobalthexacarbonyl complex of vinylacetylene, (ii) the diastereoselective Grignard reaction at the carbonyl group of the formed adducts; and (iii) the Pauson–Khand cyclization of 1,6- or 1,7-enyne precursors thus prepared. |
---|---|
ISSN: | 0959-9436 |
DOI: | 10.1016/j.mencom.2008.07.011 |