Mixed bilayers of phosphatidylcholine with dialkylaminostyrylhetarene dyes for AChE-assisted fluorescent sensing of paraoxon

• Published in: Journal of molecular liquids Vol. 366; p. 120270
• Main Authors: Elistratova, Julia G., Akhmadeev, Bulat S., Islamova, Liliya N., Fazleeva, Guzel M., Kalinin, Alexey A., Orekhov, Anton S., Petrov, Konstantin A., Sinyashin, Oleg G., Mustafina, Asiya R.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.11.2022
• Subjects: Acetylcholine; Acetylcholinesterase; Dyes; Paraoxon; pH-sensor; Phosphatidylcholine bilayers; pH-sensor; Acetylcholine; Dyes; Acetylcholinesterase; Phosphatidylcholine bilayers; Paraoxon

[Display omitted] •pH-sensitive fluorescence of dyes incorporated into phosphatidylcholine (PC)-based bilayers.•Dye’s structure optimization for sensitivity to the acidification arisen from AChE-catalyzed hydrolysis of ACh.•Monitoring of the hydrolysis process via dye-PC bilayers is affected by thei...