Metal-free tetrahydrofuranylation of alcohols with tertbutyl nitrite

• Published in: Tetrahedron letters Vol. 61; no. 34; pp. 152251 - 152253
• Main Authors: Bi, Kang, Cai, Yue-Ming, Zhou, Yun-Bing, Lin, Junyue, Liu, Miao-Chang
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 20.08.2020; Elsevier
• Subjects: Alkoxyl radical; Chemistry; Chemistry, Organic; Metal-free tetrahydrofuran; Physical Sciences; Protection of alcohols; Science & Technology; Tertbutyl nitrite; Alkoxyl radical; Protection of alcohols; Tertbutyl nitrite; Metal-free tetrahydrofuran; MILD; EFFICIENT CATALYST; TETRAHYDROPYRANYLATION; DEPROTECTION; DIRECT FACILE TETRAHYDROFURANYLATION

[Display omitted] •The protection of alcohols.•Synthesizing asymmetric ethers via tBuONO-promoted oxidative coupling between tetrahydrofuran and alcohols.•Exploring the potential applications of tertbutyl nitrite in the organic synthesis. Metal-free tetrahydrofuranylation of alcohols in the presence...