Optimization of the in-line X-ray phase-contrast imaging setup considering edge-contrast enhancement and spatial resolution

• Published in: Chinese physics C Vol. 36; no. 3; pp. 267 - 274
• Main Author: 贾全杰 陈雨 黎刚 姜晓明
• Format: Journal Article
• Language: English
• Published: 01.03.2012
• Subjects: Approximation; Biological effects; Image detection; Imaging; Insects; Optimization; Spatial resolution; X-rays; X射线源; 优化设置; 北京同步辐射装置; 对比度; 成像系统; 探测器; 相衬成像; 空间分辨率
• DOI: 10.1088/1674-1137/36/3/014
• ISSN: 1674-1137

Employing the approximation theory based on refraction and the definition of the total pointspread-function of the imaging system, the variation in the edge contrast of simple model samples is discussed with different source-to-sample and sample-to-detector distances, which actually means different spatial resolutions of the imaging system. The experiments were carried out with the Beamline 4W1A imaging setup at the Beijing Synchrotron Radiation Facility for simple model and insect samples. The results show that to obtain clear phase-contrast images of biologic tissues for the X-ray in-line imaging setup, with determined parameters such as the size of the X-ray source, the pixel size of the detector and the fixed source-to-sample distance, there is a range of optimized sample-to-detector distances. The analysis method discussed in this article can be helpful in optimizing the setup of X-ray in-line phase-contrast imaging.