Efficient one-pot synthesis of substituted 2-amino-1,3,4-oxadiazoles

• Published in: Tetrahedron letters Vol. 49; no. 47; pp. 6709 - 6711
• Main Authors: Piatnitski Chekler, Eugene L., Elokdah, Hassan M., Butera, John
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 17.11.2008; Elsevier
• Subjects: Chemistry; Chemistry, Organic; Kinase inhibitor; One-pot cyclization; Oxadiazole; Physical Sciences; Science & Technology; Oxadiazole; Kinase inhibitor; One-pot cyclization; ACID; DERIVATIVES

A convenient one-pot method for the preparation of substituted 2-amino-1,3,4-oxadiazoles is described. A convenient one-pot method for the preparation of substituted 2-amino-1,3,4-oxadiazoles has been developed. The method is a significant improvement over previously reported syntheses. Reaction of...