Comparison of Serum Triiodothyronine with Biomarkers for Alzheimer's Disease Continuum in Euthyroid Subjects

• Published in: Journal of Alzheimer's disease Vol. 85; no. 2; p. 605
• Main Authors: Ge, Feifei, Dong, Lin, Zhu, Donglin, Lin, Xingjian, Shi, Jingping, Xiao, Ming
• Format: Journal Article
• Language: English
• Published: Netherlands 01.01.2022
• Subjects: Aged; Alzheimer Disease - metabolism; Alzheimer Disease - physiopathology; Biomarkers - blood; Biomarkers - cerebrospinal fluid; Cognitive Dysfunction - metabolism; Cross-Sectional Studies; Female; Humans; Logistic Models; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; ROC Curve; Thyroid Function Tests; Thyrotropin - blood; Thyrotropin - cerebrospinal fluid; Thyrotropin - metabolism; Triiodothyronine - blood; Triiodothyronine - cerebrospinal fluid; amyloid-β; Alzheimer’s disease; thyroid hormone; biomarkers; cerebrospinal fluid

Accumulating studies have implicated thyroid dysfunction in the pathogenesis of Alzheimer's disease (AD). This study aimed to explore the association between thyroid hormone (TH) levels and cerebrospinal fluid (CSF) biomarkers for AD continuum among euthyroid subjects. In all, 93 clinically eut...