Altered Expression Profile of Circular RNAs in the Serum of Patients with Diabetic Retinopathy Revealed by Microarray

• Published in: Ophthalmic research Vol. 58; no. 3; p. 176
• Main Authors: Gu, Yonghao, Ke, Genjie, Wang, Lin, Zhou, Enliang, Zhu, Kai, Wei, Yingying
• Format: Journal Article
• Language: English
• Published: Switzerland 01.01.2017
• Subjects: Aged; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Diabetic Retinopathy - blood; Diabetic Retinopathy - etiology; Diabetic Retinopathy - genetics; Female; Gene Expression Regulation; Humans; Male; Microarray Analysis; Middle Aged; Real-Time Polymerase Chain Reaction; RNA - biosynthesis; RNA - genetics; Microarray; Diabetic retinopathy; Circular RNA

Diabetic retinopathy (DR) is the leading cause of blindness among working age adults. Circular RNAs (circRNAs) are a kind of noncoding RNAs that are involved in the development of some diseases. Here, we aimed to determine the possible role of circRNAs in the pathogenesis of DR by determining the ex...