CD44 receptor targeted ‘smart’ multi-walled carbon nanotubes for synergistic therapy of triple-negative breast cancer

• Published in: Colloid and interface science communications Vol. 35; p. 100235
• Main Authors: Singhai, Nidhi Jain, Maheshwari, Rahul, Ramteke, Suman
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.03.2020
• Subjects: Doxorubicin; Hyaluronic acid; Multi-walled carbon nanotubes; Synergistic anticancer therapy; Targeted chemotherapy; α-Tocopheryl succinate; Synergistic anticancer therapy; α-Tocopheryl succinate; Multi-walled carbon nanotubes; Hyaluronic acid; Doxorubicin; Targeted chemotherapy

Triple-negative breast cancer requires high treatment specificity and efficacy due to its aggressive nature. In the present investigation, multi-walled carbon-nanotubes (MWCNTs) were functionalized using Hyaluronic acid (HA) and α-Tocopheryl succinate (α-TOS) and loaded with Doxorubicin (Dox) to obt...