TESLA Trial: Rationale, Protocol, and Design

• Published in: Stroke: vascular and interventional neurology Vol. 3; no. 4
• Main Authors: Zaidat, Osama O., Kasab, Sami Al, Sheth, Sunil, Ortega‐Gutierrez, Santiago, Rai, Ansaar T., Given, Curtis A., Grandhi, Ramesh, Mokin, Maxim, Katz, Jeffrey M., Maud, Alberto, Gupta, Rishi, Smith, Wade S., Dippel, Diederik W., Gress, Daryl, Nguyen, Thanh N., Brown, Scott, Jadhav, Ashutosh P., Eljovich, Lucas, Majoie, Charles, Patterson, Mary S., Slight, Hannah, Below, Kristine, Yoo, Albert J.
• Format: Journal Article
• Language: English
• Published: Phoenix Wiley Subscription Services, Inc 01.07.2023; Wiley
• Subjects: clinical trial; Design; Expected utility; Ischemia; large‐core infarct; large‐vessel occlusion; Stroke; TESLA trial; Tomography

BackgroundMechanical thrombectomy has been shown to be effective in patients with acute ischemic stroke secondary to large‐vessel occlusion and small to moderate infarct volume. However, there are no randomized clinical trials for large‐core infarct volume comparing mechanical thrombectomy to medica...