Generation of an induced pluripotent stem cell (iPSC) line (JUCTCi017-A) from a patient with limb-girdle muscular dystrophy (LGMD) due to a homozygous p.Lue287Ser fs14 mutation in the SGCB gene

• Published in: Stem cell research Vol. 54; p. 102358
• Main Authors: Ababneh, Nidaa A., Barham, Raghda, Al-Kurdi, Ban, Ali, Dema, Sharar, Nour, Al Hadidi, Sabal, Alatoom, Renata M., Zalloum, Suzan, Gharandouq, Mohammad H., Makahleh, Leen, Alnsour, Leena N., Alshahwan, Hebah, El-Khateeb, Mohammed, Awidi, Abdalla
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.07.2021; Elsevier

Limb-girdle muscular dystrophies (LGMDs) are a large group of heterogenous genetic diseases characterized by muscle weakness. In this study, an induced pluripotent stem cell (iPSC) line was generated from LGMD patient’s skin dermal fibroblasts, carrying a homozygous mutation in the Sarcoglycan Beta...