Peptide-based electrochemical sensor with nanogold enhancement for detecting rheumatoid arthritis

• Published in: Talanta (Oxford) Vol. 236; p. 122886
• Main Authors: Lin, Ching-Yu, Nhat Nguyen, Uyen Thi, Hsieh, Han-Yun, Tahara, Hidetoshi, Chang, Yu-Sheng, Wang, Bing-Yu, Gu, Bing-Chen, Dai, Yu-Han, Wu, Chia-Che, Tsai, I-Jung, Fan, Yu-Jui
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.01.2022
• Subjects: autoantibodies; Autoantibody; diagnostic techniques; dielectric spectroscopy; Electrochemical impedance spectroscopy (EIS); electrodes; Nanogold; Peptide; peptides; Rheumatoid arthritis; sensors (equipment); Autoantibody; Electrochemical impedance spectroscopy (EIS); Peptide; Nanogold; Rheumatoid arthritis

Rheumatoid arthritis (RA), an autoimmune and chronic inflammatory disorder, is an incurable disease. We developed a peptide-based electrochemical sensor using electrochemical impedance spectroscopy that can be used to detect autoantibodies for RA diagnostics. We first validated that the developed pe...