Urinary volatile Organic compounds in non-alcoholic fatty liver disease (NAFLD), type two diabetes mellitus (T2DM) and NAFLD-T2DM coexistence

• Published in: Metabolomics Vol. 18; no. 12; p. 98
• Main Authors: Cozzolino, Rosaria, De Giulio, Beatrice, Martignetti, A, Forte, G, Dallio, M, Romeo, M, Scognamiglio, F, Ventriglia, L, Stocchero, M, Federico, A
• Format: Journal Article
• Language: English
• Published: New York Springer US 28.11.2022; Springer Nature B.V
• Subjects: Biochemistry; Biomedical and Life Sciences; Biomedicine; Biopsy; Cell Biology; Coexistence; Developmental Biology; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 2; Fatty liver; Gas chromatography; Headspace; Humans; Investigations; Life Sciences; Liver diseases; Mass spectroscopy; Metabolomics; Molecular Medicine; Non-alcoholic Fatty Liver Disease; Original Article; Physicochemical properties; Prospective Studies; Solid phase methods; VOCs; Volatile Organic Compounds; Volatiles; Solid-phase micro-extraction; Gas chromatography–mass spectrometry (GC-MS); Type two diabetes mellitus (T2DM); Non-alcoholic fatty liver disease (NAFLD); Volatile organic compounds (VOCs)

Introduction Accumulating evidence have shown a significant correlation between urinary volatile organic compounds (VOCs) profile and the manifestation of several physiological and pathological states, including liver diseases. Previous studies have investigated the urinary metabolic signature as a...