Enhanced 2,3-butanediol recovery from fermentation broth: a study on isobutanol/sodium chloride aqueous two-phase systems

• Published in: Biotechnology and bioprocess engineering Vol. 30; no. 3; pp. 562 - 572
• Main Authors: Gawal, Pramod Madhukar, Lataye, Sweta
• Format: Journal Article
• Language: English
• Published: Seoul The Korean Society for Biotechnology and Bioengineering 01.06.2025; Springer Nature B.V; 한국생물공학회
• Subjects: Binary systems; Biotechnology; Butanediol; Chemistry; Chemistry and Materials Science; Chloride; Chlorine compounds; Distillation; Fermentation; Industrial and Production Engineering; Industrial production; Inorganic salts; Isobutanol; Recovery; Research Paper; Response surface methodology; Sodium; Sodium chloride; Solvents; 생물공학; Distillation; Process optimization; 2,3-Butanediol recovery; Fermentation broth; Commercial potential; Aqueous two-phase extraction

The extraction and recovery of 2,3-butanediol (2,3-BD) from the fermentation broth (FB) is a significant bottleneck in industrial production. Herein, we explore the hybrid aqueous two-phase extraction combined with distillation (HATPED) for recovering 2,3-BD from FB. Aqueous two-phase systems (ATPS)...