RIFM fragrance ingredient safety assessment, hexyl octanoate, CAS Registry Number 1117-55-1

•Hexyl octanoate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.

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Published inFood and chemical toxicology Vol. 183; p. 114292
Main Authors Api, A.M., Belsito, D., Botelho, D., Bruze, M., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Fryer, A.D., Jones, L., Joshi, K., Kumar, M., Lapczynski, A., Lavelle, M., Lee, I., Liebler, D.C., Moustakas, H., Na, M., Penning, T.M., Ritacco, G., Romine, J., Sadekar, N., Schultz, T.W., Selechnik, D., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.03.2024
Subjects
Caprylates - toxicity
Odorants
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Abstract •Hexyl octanoate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.
AbstractList •Hexyl octanoate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.
ArticleNumber 114292
Author Botelho, D.
Liebler, D.C.
Sadekar, N.
Sullivan, G.
Fryer, A.D.
Joshi, K.
Na, M.
Burton, G.A.
Thakkar, Y.
Romine, J.
Tokura, Y.
Bruze, M.
Cancellieri, M.A.
Selechnik, D.
Kumar, M.
Ritacco, G.
Sipes, I.G.
Belsito, D.
Schultz, T.W.
Dekant, W.
Deodhar, C.
Lee, I.
Penning, T.M.
Siddiqi, F.
Api, A.M.
Lapczynski, A.
Jones, L.
Dagli, M.L.
Moustakas, H.
Lavelle, M.
Chon, H.
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  surname: Liebler
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  surname: Penning
  fullname: Penning, T.M.
  organization: Member of Expert Panel for Fragrance Safety, University of Pennsylvania, Perelman School of Medicine, Center of Excellence in Environmental Toxicology, 1316 Biomedical Research Building (BRB) II/III, 421 Curie Boulevard, Philadelphia, PA, 19104-3083, USA
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Snippet •Hexyl octanoate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were...
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SubjectTerms Caprylates - toxicity
Odorants
Title RIFM fragrance ingredient safety assessment, hexyl octanoate, CAS Registry Number 1117-55-1
URI https://dx.doi.org/10.1016/j.fct.2023.114292
https://www.ncbi.nlm.nih.gov/pubmed/38049056
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